Pharmaceutical Chemical Sitagliptin Intermediate CAS 486460 -32-6 Sitagliptin Phosphate

Model NO.
xusen
Colour
White
Price
Wholesale Price
MOQ
1g
Destination
Us, Europe, Asia
Brand
Xusen
Factory
Yes
Purity
99%
Payment
Bitcoins and Usdt
Customs Issues
No
Delivery
5 Days After Confirmation
Sample
for Free
Other Name
Sitagliptin Phosphate
Grade
Medicine Grade
Transport
by Air or by Sea
Use
Food
Name
Sitagliptin
Transport Package
1g, 5g, 10g
Specification
customized
Trademark
Xusen
Origin
China
HS Code
2933000000
Production Capacity
14680kg Per Month
Reference Price
Please contact us for quote
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Product Description

 
 
High Quality Pharmaceutical Chemicals Sitagliptin CAS 486460-32-6
 
 
 
 
Product Name:  Sitagliptin 
CAS No.:  486460-32-6
Molecular Formula: C16H15F6N5O
Molecular Weight: 407.3136
Property: White powder
Assay: 99%
Package: 25kg/drum

Introduction

1. Sitagliptin is an oral antihyperglycemic of the dipeptidyl peptidase-4  inhibitor class. This enzyme-inhibiting drug is used either alone or in combination with other oral antihyperglycemic agents for treatment of diabetes mellitus type

2.The benefit of this medicine is its fewer side effects in the control of blood glucose values. While safety is its advantage, efficacy is often challenged as it is often recommended to be combined with other agents such as metformin.

 
 
 
 

Introduction
 

Product Name:    Glimepiride
Synonyms:     AMARYL;3-ETHYL-2,5-DIHYDRO-4-METHYL-N-[2-[4-[[[[(TRANS-4-METHYLCYCLOHEXYL)AMINO]CARBONYL]AMINO]SULFONYL]PHENYL]ETHYL]-2-OXO-1H-PYRROLE-1-CARBOXAMIDE;3-ETHYL-2,5-DIHYDRO-4-METHYL-N-[2-[4-[[[[(TRANS-4-METHYLCYCLOHEXYL)AMINO]CARBONYL]AMINO]SULFONYL]PHENYL]ETHYL]-2-OXO-1H-PYRROLE-1-CARBOXYAMIDE;Gliclazide(diamicrChemicalbookon);CLIMEPIRIDE;Glimpiride;trans-3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methyleyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide;3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxyamide
CAS No.    93479-97-1
Formula:    C24H34N4O5S
Formula Weight:    490.62
Apperance:    Powder
Color:     Off-White 
Solubility:    DMSO: >10 mg/mL
Storage:     Room temp
Standard:     USP/CP/JP/IH

Function of Pitavastatin Calcium:
 
Like the other statins, pitavastatin is indicated for hypercholesterolaemia (elevated cholesterol) and for the prevention of cardiovascular disease.
 
A 2009 study of the 104 week LIVES trial found pitavastatin increased HDL cholesterol, especially in patients with HDL lower than 40 mg/dL, who had a 24.6% rise, in addition to greatly reducing LDL cholesterol 31.3%.HDL improved in patients who switched from other statins and rose over time. In the 70-month CIRCLE observational study, pitavastatin increased HDL more than atorvastatin.
 
It has neutral or possibly beneficial effects on glucose control. As a consequence, pitavastatin is likely to be appropriate for patients with metabolic syndrome plus high LDL, low HDL and diabetes mellitus.

Application:
  Common statin-related side effects (headaches, stomach upset, abnormal liver function tests and muscle cramps) were similar to other statins. However, pitavastatin seems to lead to fewer muscle side effects than certain statins that are lipid-soluble, as a result of the fact that pitavastatin is water-soluble (as is pravastatin, for example). One study found that coenzyme Q10 was not reduced as much as with certain other statins (though this is unlikely given the inherent chemistry of the HMG-CoA reductase pathway that all statin drugs inhibit).
 
Pitavastatin appears to have improved tolerably in its metabolic profile, with a neutral effect on glucose regulation, as opposed to many statins.
 
As opposed to other statins, there is evidence that pitavastatin improves insuli resistance in humans, with insuli resistance assessed by the homeostatic model assessment (HOMA-IR) method.
 
Hyperuricemia or increased levels of serum uric acid have been reported with pitavastatin.
 
If you are interested in our products or have any questions, please feel free to contact us!
 
Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.
 
Get free sample: W e can provide 1g free sample for you to test. You can place an order formally after confirming that the product quality meets your requirements.

 
About Transportation

The transportation time is 7-15 days. Safe Customs Clearance, door to door Service.
We always take extra care in packing and delivery. Even so, some customers still worry about the loss of packages and other problems. We understand your concerns. We have been engaged in foreign trade for more than ten years and have good after-sales service and reshipment policy. You can purchase with confidence.

Contact us       We will give you the best price according to your purchase volume


Pharmaceutical Chemical Sitagliptin Intermediate CAS 486460-32-6 Sitagliptin Phosphate Pharmaceutical Chemical Sitagliptin Intermediate CAS 486460-32-6 Sitagliptin Phosphate
Pharmaceutical Chemical Sitagliptin Intermediate CAS 486460-32-6 Sitagliptin Phosphate
 
 
 

Factory Price
Pharmaceutical Chemical Sitagliptin Intermediate CAS 486460-32-6 Sitagliptin Phosphate
 
NO CUSTOMS ISSUE
 
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Q: How to start orders or make payments?

A:You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by Trade Manager, and
we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

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A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the  samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q: What's your MOQ?

A:For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low price product, our MOQ starts  from 100g and 1kg.

Q: Is there a discount?

A: Yes, for larger quantity, we always support with better price.

Q:How do you treat quality complaint?

First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we
will send you free goods for replacement or refund your loss.

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Organic Intermediate