Hot Sale 5-Aminosalicylic Acid CAS 89-57-6 Tratment Of Ulcerative Colitis

Product Name:    5-Aminosalicylic acid
Synonyms:    5-Aminosalicylic acid, 98.5%, IKK inhibitor;2-HYDROXY-5-AMINOBENZOIC ACID;3-Carboxy-4-hydroxyaniline;5-AMINO-2-HYDROXYBENZOIC ACID;5-AMINOSALICYLIC ACID;5-ASA;5-AS;rowasa
CAS:    89-57-6
MF:    C7H7NO3
MW:    153.14
EINECS:    201-919-1
Product Categories:    API;CITANEST;Pharmaceuticals;Carboxylic Acids;Aromatics;Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Carboxylic Acids;Phenyls & Phenyl-Het;Organic acids;Various Metabolites and Impurities;Fendosal;Intermediates & Fine Chemicals;Phenyls & Phenyl-Het;Fluorescent;FINE Chemical & INTERMEDIATES;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Metabolites & Impurities
Mol File:    89-57-6.mol


Mesalazine is an anti-inflammatory agent, structurally related to the salicylates, which is active in inflammatory bowel disease. It is considered to be the active moiety of sulphasalazine. A study of the therapeutic properties of sulfasalazine and its constituents[mesalazine (5-amino salicylic acid, 5-ASA) and sulfapyridine] indicated that mesalazine is the therapeutically active component, while sulfapyridine acts as an inert carrier molecule to facilitate delivery to the colon.[2] This discovery, coupled with the implication of sulfapyridine in most of the adverse events associated with sulfasalazine treatment,[3] led to the development of Mesalazine as a pure therapeutic entity.

5-Aminosalicylic Acid CAS 89-57-6  of Chemical Properties
Melting point     275-280 °C (dec.) (lit.)
Boiling point     276.03°C (rough estimate)
density     1.3585 (rough estimate)
vapor pressure     0Pa at 25ºC
refractive index     1.5500 (estimate)
Fp     279-281°C
storage temp.     2-8°C
solubility     Soluble in dimethyl sulfoxide.
form     tablets
pka    2.74, 5.84(at 25ºC)
color     off-white to gray
PH    4.0-4.1 (0.8g/l, H2O, 20ºC)
PH Range    Non-B uorescence (3.1) to light green B uorescence (4.4)
Water Solubility     <0.1 g/100 mL at 21 ºC
Decomposition     279-281 ºC
Merck     14,5904
BRN     2090421
Stability:    Stable. Incompatible with acids, acid anhydrides, acid chlorides, chloroformates, strong oxidizing agents.
Major Application    Detergent, hair dyes, prevention of colorectal cancer, treating inflammatory bowel disease, autoimmune disorders, gastrointestinal inflammation, chemokine-mediated diseases, mucosal tissue disorder, sleep disorders, rectoanal tenesmus, ulcerative colitis
InChIKey    KBOPZPXVLCULAV-UHFFFAOYSA-N
LogP    0.98 at 25ºC
CAS DataBase Reference    89-57-6(CAS DataBase Reference)
NIST Chemistry Reference    Mesalamine(89-57-6)
EPA Substance Registry System    Benzoic acid, 5-amino-2-hydroxy- (89-57-6)

Function and Application of  5-Aminosalicylic Acid CAS 89-57-6

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.