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Meglumine; CAS 6284-40-8

Colour
White
Shelf Life
2 Years
Lead Time
5-7 Working Days
Transport
Air/Express/Sea
Site Audit
Available
MOQ
10g
Certificates
ISO9001/SGS
Stocks
in Stock
Package
1kg/5kg/10kg/25kg
Purity
99%
Samples
Available
Transport Package
Drum/Bottle/Bags
Trademark
Yunbang
Origin
China
Reference Price
Please contact us for quote
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Product Description

Meglumine;CAS 6284-40-8
 
Meglumine; CAS 6284-40-8
 
 
Meglumine Chemical Properties
Melting point  129-131.5 °C (lit.)
alpha  -16.5 º (c=10, H2O, on dry sub)
Boiling point  331.88°C (rough estimate)
density  1.2669 (rough estimate)
refractive index  -16.5 ° (C=2, H2O)
RTECS  LZ4295770
storage temp.  2-8°C
solubility  H 2 O: 0.1 g/mL, clear, colorless
pka pKa 9.39(H2O,t =30.0,I=0.05N2)(Approximate)
form  Crystalline Powder
color  White to almost white
PH 11 (10g/l, H2O, 20ºC)
optical activity [α]20/D 16.5±0.5°, c = 2% in H2O
Water Solubility  100 g/100 mL (25 ºC)
Sensitive  Air Sensitive & Hygroscopic
Merck  14,6078
BRN  385906
InChIKey MBBZMMPHUWSWHV-VZFHVOOUSA-N
NIST Chemistry Reference N-methylglucamine(6284-40-8)
EPA Substance Registry System Meglumine (6284-40-8)
 
Safety Information
Risk Statements  36/37/38
Safety Statements  24/25
WGK Germany  3
F  3-10-23
Autoignition Temperature ~662 °F
TSCA  Yes
HS Code  29221980
Toxicity LD50 orally in Rabbit: > 5000 mg/kg
Meglumine Usage And Synthesis
Chemical Properties white to almost white crystalline powder
Chemical Properties Meglumine occurs as a white to slightly yellow-colored crystalline powder; it is odorless or with a slight odor.
Uses antiinflammatory
Uses excipient in cosmetics and X-ray contrast media
Definition ChEBI: A hexosamine that is D-glucitol in which the hydroxy group at position 1 is substituted by the nitrogen of a methylamino group. A crystalline base, it is used in preparing salts of certain acids for use as diagnostic radiopaque media, whi e its antimonate is used as an antiprotozoal in the treatment of leishmaniasis.
Production Methods Meglumine is prepared by the imination of glucose and monomethylamine, in an alcoholic solution, followed by catalytic hydrogenation.
Brand name Renovue (Bracco).
Pharmaceutical Applications Meglumine is an organic base used as a pH-adjusting agent and solubilizing agent, primarily in the preparation of soluble salts of iodinated organic acids used as X-ray contrast media.
Safety Meglumine is widely used in parenteral pharmaceutical formulations and is generally regarded as a nontoxic material at the levels usually employed as an excipient. 
LD 50  (mouse, IP): 1.68 g/kg
storage Meglumine does not polymerize or dehydrate unless heated above 150°C for prolonged periods.
The bulk material should be stored in a well-closed container in a cool, dry place. Meglumine should not be stored in aluminum containers since it reacts to evolve hydrog en gas; it discolors if stored in containers made from copper or copper alloys. Stainless steel containers are recommended.
Purification Methods Crystallise N-methyl-D(-)-glucamine from MeOH. Its solubility in H2O is 10%. [Karrer & Herkenrath Helv Chim Acta 20 83 1957 also for other N-alkyl derivatives, Beilstein 4 IV 1914.]
Incompatibilities Incompatible with aluminum, copper, mineral acids, and oxidizing materials. Differential scanning calorimetry studies suggest meglumine is incompatible with glipizide.
Regulatory Status Included in the FDA Inactive Ingredients Database (injections; oral tablets). Included in parenteral medicines licensed in the UK.
Meglumine; CAS 6284-40-8 Meglumine; CAS 6284-40-8
Meglumine; CAS 6284-40-8 Meglumine; CAS 6284-40-8 Company Informations:

Hunan Yunbang Pharmaceutical Co., Ltd. ( Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".

We can provide customers with customized processing, research and development services;
We can develop high-end Pharmaceutical and chemical products with high technical difficulties,high barriers and unique production processes;
We can provide 100 grams Grade, kilograms, and hundred kilograms of raw material pharmaceutical intermediates and other products.
We can perform -100°C to 300°C reaction.

R&D strength is the company's core competitiveness.Yunbangpharm has maintains a good cooperation relationship with many Universities and Research institutes locally, which can quickly transform R&D results into industrial production.

Our goal : To achieve the integrated upgrade of P harmaceutical intermediates, raw materials and high-end chemical products, adhere to "serving pharmaceutical companies, creating our brands" to provide customers with high-quality and low-cost pharmaceutical and chemical products, realizing Win-win cooperation and common developmen

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