Chemical Properties
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light brown powder
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Uses
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Triphenylmethane is a triarylmethane compound used as the backbone of synthetic dyes. Triphenylmethane has also been shown to inhibit 3-methylcholanthrene-induced neoplastic transformation of 10T1/2 cells.
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Definition
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ChEBI: A triarylmethane in which the three aryl groups are phenyl. It forms the basic skeleton of several synthetic dyes.
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Synthesis Reference(s)
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Journal of the American Chemical Society, 73, p. 5846, 1951
DOI:
10.1021/ja01156a116
Organic Syntheses, Coll. Vol. 1, p. 548, 1941
Tetrahedron Letters, 21, p. 801, 1980
DOI:
10.1016/S0040-4039(00)71509-7
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Purification Methods
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Crystallise triphenylmethane from EtOH or *benzene (with one molecule of *benzene of crystallisation which is lost on exposure to air or by heating on a water bath). It can also be sublimed under vacuum. It has been given a preliminary purification by refluxing with tin and glacial acetic acid, then filtered hot through a glass sinter disc, and precipitated by addition of cold water. [Beilstein 5 H 698, 5 IV 2495.]
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