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Boc- (R) -3-Amino-4- (2, 4, 5-Trifluoro-Phenyl) - Butyric Acid CAS486460-00-8

Colour
White
Shelf Life
2 Years
Lead Time
5-7 Working Days
Transport
Air/Express/Sea
Site Audit
Available
MOQ
10g
Certificates
ISO9001/SGS
Stocks
in Stock
Package
1kg/5kg/10kg/25kg
Purity
99%
Samples
Available
Transport Package
Drum/Bottle/Bags
Trademark
Yunbang
Origin
China
Reference Price
Please contact us for quote
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Product Description

Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS486460-00-8
 
Boc- (R) -3-Amino-4- (2, 4, 5-Trifluoro-Phenyl) -Butyric Acid CAS486460-00-8
Melting point  136-138ºC
Boiling point  443.1±45.0 °C(Predicted)
density  1.292±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,2-8°C
pka 4.30±0.10(Predicted)
Physical Form White to Yellow Solid
Description Boc-(R) -3-amino-4 -(2,4, 5-trifluorophenyl) butyric acid is an important intermediate for the preparation of sitagliptin. Sitagliptinphosphate is the first dipeptidase -IV(dpp-4) inhibitor approved by FDA in 2006. It is used for the treatment of type II diabetes mellitus. It has obvious hypoglycemic effect when used alone or in combination with metformin and pioglitazone, and it is safe to take, well tolerated, with few adverse reactions.
Uses (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid has been used as a reactant for the preparation of dipeptidyl peptidase-4 (DPP4) inhibitors for the treatment of type 2 diabetes, such as sitagliptin.
 
Boc- (R) -3-Amino-4- (2, 4, 5-Trifluoro-Phenyl) -Butyric Acid CAS486460-00-8
Boc- (R) -3-Amino-4- (2, 4, 5-Trifluoro-Phenyl) -Butyric Acid CAS486460-00-8 Boc- (R) -3-Amino-4- (2, 4, 5-Trifluoro-Phenyl) -Butyric Acid CAS486460-00-8 Boc- (R) -3-Amino-4- (2, 4, 5-Trifluoro-Phenyl) -Butyric Acid CAS486460-00-8 Company Informations:

Hunan Yunbang Pharmaceutical Co., Ltd. ( Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".

We can provide customers with customized processing, research and development services;
We can develop high-end Pharmaceutical and chemical products with high technical difficulties,high barriers and unique production processes;
We can provide 100 grams Grade, kilograms, and hundred kilograms of raw material pharmaceutical intermediates and other products.
We can perform -100°C to 300°C reaction.

R&D strength is the company's core competitiveness.Yunbangpharm has maintains a good cooperation relationship with many Universities and Research institutes locally, which can quickly transform R&D results into industrial production.

Our goal : To achieve the integrated upgrade of P harmaceutical intermediates, raw materials and high-end chemical products, adhere to "serving pharmaceutical companies, creating our brands" to provide customers with high-quality and low-cost pharmaceutical and chemical products, realizing Win-win cooperation and common developmen

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