High Purity Anticonvulsant Drug Carbamazepine Carbamazepin and Tegretol CAS 298-46-4
Carbamazepine Basic information
Product Name:
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Carbamazepine
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Synonyms:
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Oxcarbazepine IMpurity A;CarbaMazepine (D10, 98%);CarbaMazepine (D10, 98%) 100 ug/Ml In CH3CN-D3;CarbaMazepine (D10, 98%) 100 ug/Ml In MeOH;CarbaMazepine-13C6;Carbamazepine solution ;CARBAMAZEPIN;CARBAMAZEPINE
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CAS:
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298-46-4
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MF:
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C15H12N2O
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MW:
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236.27
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EINECS:
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206-062-7
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Product Categories:
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TEGRETOL;Pharmaceutical raw material;Pharmaceutical Chemicals;Intermediates & Fine Chemicals;Aromatics;Isotope Labelled Compounds;Pharmaceutical;Acids and Derivatives;Heterocycles;Active Pharmaceutical Ingredients;APIs;Pharmaceuticals
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Carbamazepine Chemical Properties
Melting point
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191-192 °C (lit.)
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Boiling point
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378.73°C (rough estimate)
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density
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1.1099 (rough estimate)
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refractive index
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1.5906 (estimate)
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Fp
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9ºC
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storage temp.
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2-8°C
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solubility
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45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble29mg/mL
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pka
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13.94±0.20(Predicted)
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form
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Crystals
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color
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Almost white
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Water Solubility
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pract. insoluble
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Merck
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14,1781
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CAS DataBase Reference
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298-46-4(CAS DataBase Reference)
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NIST Chemistry Reference
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Carbamazepine(298-46-4)
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EPA Substance Registry System
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5H-Dibenz[b,f]azepine-5-carboxamide (298-46-4)
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Carbamazepine Chemical Properties
White Solid
Carbamazepine Chemical Properties
1. analgesic, anticonvulsant
2. Used in treatment of pain associated with trigeminal neuralgia. Anticonvulsant
3. Carbamazepine (CBZ) is a first generation anticonvulsant and mood stabilizing compound that has been used as a therapeutic in the context of neuropathic pain, epilepsy, and affective disorders. It exerts its effects by blocking voltage-gated sodium channels (IC50 = 640 μM), making fewer of these channels available to subsequently open, which leads to decreased high-frequency repetitive firing of action potentials. The estimated IC50 values for inhibition of Nav1.7-, Nav1.3-, and Nav1.8-type channels by CBZ following prolonged inactivation have been reported as 406, 900, and 138 μM, respectively. CBZ can also inhibit L-type Ca2+ channels (IC50 = 974 μM) and has been shown to potentiate GABAA receptors (IC50 >3 mM).
Definition ChEBI: A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Carbamazepine Clinical Use
Carbamazepine is an effective agent for the treatment of partial seizures and generalized tonic-clonic seizures; its use is contraindicated in absence epilepsy. Carbamazepine is also useful in the treatment of trigeminal neuralgia and is an effective agent for the treatment of bipolar disorders.
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Product Pictures
Our Factory
Xingtai Xingjiu New Material Technology Co., Ltd. was founded in 2023 and located in Xingtai City, Hebei Province.Our company aims to be a leading materials science company in innovation, customer orientation, inclusiveness and sustainability, committed to the sustainable development of society through our expertise in materials science and deep collaboration with our customers.
Xingjiu company products industrial intermediates, cosmetics raw materials, solvents and other daily chemical raw materials, to provide customers with a wide range of technology based differentiated products and right solutions.Our goal is to become a leading manufacturer of chemicals.With vigorous and progressive spirit and strong competitive strength, the company will strive to provide customers with high quality industrial products and excellent service, in order to achieve the lofty goals.
Xingjiu company adheres to the four core values of customer first, team building, innovation and responsibility to achieve the common development of the company and the society.If you are interested in our products, please send us emails or call us.We will get back to you in time.
Packing and Shipping
1. 1kg with double plastic container inside/Aluminum foil bag .
2. 25kg with double plastic container inside/Fiber drum outside.Or as your request.
3. Shipped in 3 days after payment.
1.Stored in a cool and dry well-closed container and in ventilated area.
2.kept away from moisture and strong light or high temperature.
3.Two years under well storage situation and stored away from direct sun light.
Payment Term
Why Choose Us
1. the customer comes first, we provide reasonable price, high quality product and prompt shipment
2. We can send the goods to your delivery address directly. it is relatively safe and fast. We have ready goods in stock.
3. quick and clear response to customers questions.
warm after sale service, we will help to solve the problems in your wusge.
4. we could make our price discount if you place a substanial order with us.
How To Proceed You Oreder:
1: Please let me know the items you are favorable, quantities, and the destination country.
2: You confirm all detail, and offer purchasing order.
3: We send the detail price of our product and offer the suitable shipping method for reference.
4: You confirm the order and pay mony 100% in advance and send us the detailed contacting information, including contacting person/company, address, mobile number, ZIP code and your special requirements.
5: We arrange the shipment according to your requirements, and tracking code will be offered after claiming the payment within 24h, then you can track your parcel at any moment.
6: We offer after-sales services after service after you receive your parcel.
FAQ
Q1.
Can I have a sample order for your products?
Yes, we welcome sample order to test and check quality. Mixed samples are acceptable.
Q2.
What about the lead time?
Sample needs 3-5 days, mass production time needs 1-2 weeks for order quantity more than
Q3.
Do you have any MOQ limit for order?
For the high value product,our MOQ starts from 1g and generally starts from 10gs.For other low price product,our MOQ starts from 100g and 1000g.
Q4:What is your carrier?
For small order,we ship by air express. For example Fedex,TNT, DHL ,EMS.
For large order,we can send by air to the air port and send by sea to the sea port.
Q5.
How do you ship the goods and how long does it take to arrive?
We usually ship by DHL, UPS, FedEx or TNT. It usually takes 3-5 days to arrive. Airline and sea shipping also optional.
Q6:How to contact us?
You can dial our telephone directly, you will get our reply.
Or send email to us.
If you have any other needs, please contact me