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Manufacturer Supply High Quality CAS 59865-13-3 Cyclosporin a
Model NO.
TY-02AL
Colour
White
Assay
99%
Shelf
2 Years
Place
China
Package
Foil Bag
Transport Package
25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
Please contact us for quote
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Description
Product Description
Product name
Cyclosporin A
CAS
59865-13-3
Appearance
white powder
Assay
99%
Storage
Cool and Protect from light
Cyclosporin A
Product Name Cyclosporin A
CAS 59865-13-3
MF C62H111N11O12
MW 1202.61
EINECS 611-907-1
MOL File 59865-13-3.mol Melting point 148-151°C
alpha D20 -244° (c = 0.6 in chloroforrm); D20 -189° (c = 0.5 in methanoll)
Boiling point 838.63°C (rough estimate)
Density 0.9913 (rough estimate)
refractive index 1.6500 (estimate)
Flash point 87ºC
storage temp. -20°C
solubility ethanol: 30 mg/mL
pka 13.32±0.70(Predicted)
form solid
color white
Water Solubility Soluble in dimethyl sulfoxide and ethanol. Insoluble in water.
Usage And Synthesis
Immunosuppressants
Cyclosporin A is a lipophilic cyclic peptide compounds separated by certain Hyphomycetes fungi, such as Cylindrocarpon lucidum and Tolypocladium inflatumculture medium. In 1980s, as an immunosuppressant, it has been widely used in the world, is now used for a variety of tissues and organ transplant to prevent rejection reaction and to treat autoimmune diseases.
Cyclosporin A is a strong immunosuppressant, inhibits the onset of the reaction in cell media, reversibly inhibits T cell proliferation, does not inhibit the generation of blood cells, does not affect the function of the phagocyte. As compared with other inhibitors, fewer advantages are induce or aggravate infection, mainly used in clinical kidney, liver, heart, lung, bone marrow transplant anti-rejection, can be combined with adrenal corticosteroids, but not in combination with other immunosuppressive agents. Also used in certain autoimmune diseases (such as systemic lupus erythematosus, lupus nephritis, rheumatoid arthritis, autoimmune hemolytic anemia). Try to uveitis, severe aplastic anemia, refractory idiopathic thrombocytopenic purpura, psoriasis, etc.
GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.
Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.
Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.
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