Medicine Grade Raw Material Powder Loratadine CAS 79794-75-5 For Anti-allergic

Product Name:    Loratadine
Synonyms:    LORATADINE;LORATADINE-D5;LORATIDINE;CLARATYNE;CLARITIN;ethyl 4-(8-chloro-5,6-dihydro-11h-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate;4-(8-Chloro-10,11-dihydro-4-aza-5H-dibenzo[a,d]cycloheptene-5-ylidene)piperidine-1-carboxylic acid ethyl ester;4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine-11-ylidene)piperidine-1-carboxylic acid ethyl ester
CAS:    79794-75-5
MF:    C22H23ClN2O2
MW:    382.88
EINECS:    935-907-9
Product Categories:    Other APIs;Amines;API's;Histamine receptor;Heterocycles;Pharmaceutical intermediate;Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:    79794-75-5.mol


Loratadine, sold under the brand name Claritin among others.Loratadine(Claritin) is a long-acting, non-sedating antihistamine that is used for the treatment of allergies. Histamine is a chemical that causes many of the signs and symptoms of an allergy. Histamine is released from histamine-storing cells (mast cells) and attaches to other cells that have receptors for histamine on their surfaces. Histamine stimulates the cells to release chemicals that produce effects that we associate with allergy, including welts, itching, and tissue swelling. Loratadine(Claritin) blocks one type of histamine receptor (the H1 receptor) and thus prevents activation of cells with H1 receptors by histamine.

Loratadine CAS 79794-75-5  of Chemical Properties
Melting point     134-136°C
Boiling point     531.3±50.0 °C(Predicted)
density     1.261±0.06 g/cm3(Predicted)
RTECS     TM6129200
storage temp.     2-8°C
solubility     DMSO: 26 mg/mL, soluble
form     powder
pka    4.27±0.20(Predicted)
color     white
Water Solubility     It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloro form, and methan ol.
Merck     14,5578
Stability:    Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.
InChIKey    JCCNYMKQOSZNPW-UHFFFAOYSA-N
CAS DataBase Reference    79794-75-5(CAS DataBase Reference)
EPA Substance Registry System    1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester (79794-75-5)


Function and Application of  Loratadine CAS 79794-75-5

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.