N | Colorless or light-yellow liquid,soluble in water, alcohol and other organic solvent and insoluble in light petroleum | |||
Molecular Formula | C 4 H 6 O 3 | |||
Structural Formula | ||||
Molecular Weight | 102.09 | |||
SPECIFICATION |
A |
B | ||
Assay(HPLC) | 97% Min | 90% Min | ||
Specific Rotation (c=1,EtOH) | -84~-86 | -75+5 | ||
Opecific Purity(e.e%) | 99% Mix | 99% Mix | ||
MAIN FUNCTION AND PURPOSE | S(-)-3-Hydroxy-?í butyrolactone is an important intermediate in organic synthesis and an important chiral pool. It is mainly used in the synthesis of some natural products and some bioactive chiral drugs or antibiotic chiral drugs. For example, it is a key intermediate in synthesis of nerve regulator (R)-GABOB and brain metabolic accelerant S(-)-Oxiracetam. s-3-Hydroxy-?íbutyrolactone can be deoxidized to S(-)-3-hydroxy-tetrahydrofurane which is an important intermediate of anti-AIDS drugs. It is also used in the synthesis of S(-)-3-hydroxy-4-bromobutyric acid which is a potential stabilizer. It can also be used to produce S(-)-5-hydroxymethyl-oxazolin which is a new antibiotic drug. Besides, both S(-)-N-methyl-hydroxypyrrole and (R)-N-methyl-3-methylamino-pyrrole have important bioactivity, and they can be made from s-3-Hydroxy-?íbutyrolactone by simple reaction. Furthermore, s-3-Hydroxy-?íbutyrolactone can synthesize many natural products. | |||
PACKING | in 25kg or 200kg drum or according to customer requirement | |||
STORAGE | Kept airtightly in a light-proof, dry and cool place. |
Thanks for your considering of Hebei Guanlang Biotechnology Co., Ltd.(Crovell).Crovell is a fast growing intermediates company,Which located in Shijiazhuang,Hebei Province.
Crovell is specialized in pharmaceutical intermediate,veterinary drug intermediates and dyes intermediates,such as phenylacetamide,dimethylamine hcl, benzyl chloride etc.Crovell also supply various industrial chemicals for customers, such as citric acid,potassium chloride etc.
So far,Crovell has business in more than 35 countries,most big customers come from europe and America, because among the suppliers in china,Crovell can always make the product quality best, some of the products from Crovell can reach the purity of 99.9+, such as 2-phenylacetamide. This is the important reason for customers who choosing Crovell.
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