Melanotan I is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I can be used for sunlight-induced skin cancers research.
Product Name | (Nle4,D-Phe7)-α-MSH trifluoroacetate salt |
CAS | 75921-69-6 |
Molecular Formula | C 78 H 111 N 21 O 19 |
Appearance | White Powder |
Grade | Pharmaceutical Grade |
Specification | 99% |
Density | 1.5±0.1 g/cm3 |
Molecular Weight | 1646.845 |
Exact Mass | 1645.836548 |
PSA | 642.98000 |
LogP | -0.80 |
Index of Refraction | 1.674 |
Storage condition | −20°C |
Melanotan-1(MT-1) sometimes referred to as Afamelanotide, is a synthetic alpha-melanocyte stimulating hormone (a-MSH) peptide analog first developed at the University of Arizona and later by Clinuvel..
It acts on the melanocortin system and induces melanogenesis in human and animal trials.MT-1 can induce tanning in human volunteers who are known to tan easily in response to sunlight. Latest studies suggests that MT-1 has a highly effective for treatment of erythropoetic protoporphyria.
In the US about two-thirds of patients suffered erythropoetic protoporphyriaare receiving MT-1 as treatment, most of them claim that their symptomatic relief met expectations.
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