Density | 1.3±0.1 g/cm3 |
Boiling point | 594.4±50.0 °C at 760 mmHg |
Melting point | N/A |
Molecular formula | C 22 H 26 N 2 O 4 S |
Molecular weight | 414.518 |
Flash point | 313.3±30.1 °C |
Exact Mass | 414.161316 |
PSA | 84.38000 |
LogP | 3.63 |
Storage Condition | Sealed, cool and dry storage |
Package | Drum / Aluminum Foil Bag / According to customer's requiement |
Diltiazem is a potent vasodilator, increasing blood flow and variably decreasing the heart rate via strong depression of A-V node conduction. Its pharmacological activity is somewhat similar to verapamil, another nondihydropyridine (non-DHP) calcium channel blocker.Chemically, it is based upon a 1,4-thiazepine ring, making it a benzothiazepine-type calcium channel blocker.
It is a vasodilator of coronary and peripheral vessels, which reduces peripheral resistance and afterload, though not as potent as the dihydropyridine (DHP) calcium channel blockers. This results in minimal reflexive sympathetic changes.
Diltiazem has negative inotropic, chronotropic, and dromotropic effects. This means diltiazem causes a decrease in heart muscle contractility - how strong the beat is, lowering of heart rate - due to slowing of the sinoatrial node, and a slowing of conduction through the atrioventricular node - increasing the time needed for each beat. Each of these effects results in reduced oxygen consumption by the heart, reducing angina symptoms. These effects also reduce blood pressure by causing less blood to be pumped out.
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1.What is your shipping terms ?
Faster ways : EDEX , DHL , UPS , TNT , etc by sea or by air
2.Can you design and make as customers ' request ?
Yes , we will do as the detailed specification from the customers , and professional recommendatiop will be offered to customers .
3.What services can we provide ?
Accepted Delivery Terms : FOB , CIF , EXW
Accepted Payment Type : T / T , Bank transfer , Western union , Bitcoin .
4.What is your delivery time ?
Delivery :2-3weeks after we receive the deposit .
5.How does your factory do regarding quality control ? We do test for 3 times before packing .