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Manufacturer Supply High Quality CAS 21881-77-6 Nifedipine
Model NO.
TY-79XQ
Colour
White
Assay
99%
Shelf
2 Years
Place
China
Package
Foil Bag
Transport Package
25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
Please contact us for quote
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Description
Product Description
Product name
Nifedipine
CAS
21829-25-4
Appearance
white powder
Assay
99%
Storage
Cool and Protect from light
Nifedipine
Product Name Nifedipine
CAS 21829-25-4
MF C17H18N2O6
MW 346.33
EINECS 244-598-3
MOL File 21829-25-4.mol
Chemical Properties
Melting point 171-175 °C
Boiling point 481.08°C (rough estimate)
Density 1.2109 (rough estimate)
storage temp. 2-8°C
solubility DMSO: soluble
pka pKa -0.9/>13(DMF,t undefined) (Uncertain)
form powder
color yellow
Water Solubility <0.1 g/100 mL at 19.5 ºC
Merck 14,6528
InChIKey CYCWGQFQPAYBHG-UHFFFAOYSA-N
CAS DataBase Reference 21829-25-4(CAS DataBase Reference)
NIST Chemistry Reference Nifedipine(21829-25-4)
Usage And Synthesis
Pharmacological effects
Nifedipine is a kind of dihydropyridine calcium antagonists, it can inhibit the Ca2 + uptake of cardiac and vascular smooth muscles, and it can expand the coronary artery , increase coronary blood flow,and improve myocardial ischemic tolerance, at the same time, it can expand peripheral arteries and reduce peripheral vascular resistance,and relieve coronary artery spasm, and increase coronary blood flow, improve myocardial ischemia,in order to decrease the blood pressure. Small doses do not affect blood pressure, when expanding coronary artery ,it is a better anti-angina drug .It is used for the prevention and treatment of angina pectoris,with no adverse effects on respiratory function, its efficacy is best particularly for angina pectoris coronary spasm and obstructive airway disease with angina , its efficacy is superior to β-blockers.It is also applied to all types of high blood pressure, including severe and resistant hypertension. Treatment of refractory congestive heart failure may be taking this long. It is also used for the treatment of primary pulmonary hypertension, diffuse esophageal spasm and bronchial asthma, duodenal ulcers, urinary tract obstruction, exercise-induced asthma, achalasia.
GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
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high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
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Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
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