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Manufacturer Supply High Quality CAS 5579 -84-0 Betahistine Dihydrochloride
Model NO.
TY-79XQ
Colour
White
Assay
99%
Shelf
2 Years
Place
China
Package
Foil Bag
Transport Package
25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
Please contact us for quote
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Description
Product Description
Product name
Betahistine dihydrochloride
CAS
5579-84-0
Appearance
white powder
Assay
99%
Storage
Cool and Protect from light
Betahistine dihydrochloride
Product Name Betahistine dihydrochloride
CAS 5579-84-0
MF C8H14Cl2N2
MW 209.12
EINECS 226-966-5
MOL File 5579-84-0.mol
Chemical Properties
Melting point 150-154 °C
storage temp. 2-8°C
solubility Very soluble in water, soluble in ethanol (96 per cent), practically insoluble in 2propanol.
form powder
CAS DataBase Reference 5579-84-0(CAS DataBase Reference)
Usage And Synthesis
Description
Betahistine dihydrochloride (BH.2HCl) is an orally active histamine analog which has been used to control vertigo, lack of hearing and tinnitus related to Ménière's disease. The mechanism of BH.2HCl is to reduce the pressure of the membranous labyrinth that results in enhancement of the microvasculature circulation and improves the signs of Ménière's disease. Peroral administration undergoes extensive first-pass metabolism and gastric irritation in patients with peptic ulcer. In treatment of vertigo, a uniform and constant supply of drug is required in order to maintain steady-state concentration of the drug in the body. Unfortunately, BH.2HCl possesses a short half-life of about 3-4 h and requires frequent administration of the drug,12-15 thereby making it an ideal candidate for controlled release preparations.
Chemical Properties
white to light yellow crystalline powder
Uses
Betahistine is belongs to a group of medications used to treat vertigo associated with Ménière's disease. Vertigo is a condition that causes sufferers to have a sensation of rotation or movement of themselves or their surroundings. Ménière's disease is a disorder of the inner ear that causes vertigo in addition to symptoms such as ringing in the ears, headache, and loss of hearing.
Betahistine is used to reduce the number of episodes of vertigo associated with Ménière's disease. It is believed to work by decreasing the pressure in the ear. This pressure is believed to contribute to the sense of dizziness, nausea, and ringing in the ears and hearing loss that people with Ménière's disease experience.
GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.
Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
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Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
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