(3,4-Dimethoxyphenyl)acet on trile Chemical Properties |
Melting point | 54-57 °C(lit.) |
Boiling point | 171-178 °C10 mm Hg(lit.) |
density | 1.1607 (rough estimate) |
refractive index | 1.5168 (estimate) |
Fp | >230 °F |
storage temp. | Sealed in dry,Room Temperature |
solubility | meth anol: 0.1 g/mL, clear |
form | Crystals or Crystalline Needles |
color | yellow |
Water Solubility | insoluble |
BRN | 1956100 |
InChIKey | ASLSUMISAQDOOB-UHFFFAOYSA-N |
CAS DataBase Reference | 93-17-4(CAS DataBase Reference) |
NIST Chemistry Reference | Benzeneace tonitrile, 3,4-dimethoxy-(93-17-4) |
Safety Information |
Hazard Codes | Xn,T |
Risk Statements | 22-23/24/25-36/37/38-20/21/22 |
Safety Statements | 36/37-45-22-36-26 |
RIDADR | 3276 |
WGK Germany | 3 |
RTECS | AL9325000 |
Hazard Note | Irritant |
HazardClass | IRRITANT |
HS Code | 29269090 |
(3,4-Dimethoxyphenyl)acet onitrile Usage And Synthesis |
Chemical Properties | white to almost white crystals or cryst. needles |
Uses | An Impurity of Verapamil (V125000). An intermediate in the preparation of the muscle relaxant Papverine (P190500). |
Synthesis Reference(s) |
Journal of the American Chemical Society, 57, p. 1126, 1935
DOI:
10.1021/ja01309a053
Tetrahedron Letters, 24, p. 4533, 1983 DOI: 10.1016/S0040-4039(00)85947-X |
Purification Methods | Its solubility is 10% in MeOH, and it has been recrystallised from EtOH or MeOH. Purify it also by distillation followed by recrystallisation. [Price & Rogers Org Synth Coll Vol III 174 1955, Niederl & Ziering J Am Chem Soc 64 885 1952, Julian & Sturgis J Am Chem Soc 57 1126 1935, Beilstein 10 I 198.] |