Product Description
Bupivacaine hydrochloride
Bupivacaine hydrochloride structure
|
Common Name
|
Bupivacaine hydrochloride
|
CAS Number
|
14252-80-3
|
Molecular Weight
|
324.889
|
Density
|
N/A
|
Boiling Point
|
423.4ºC at 760 mmHg
|
Molecular Formula
|
C
18
H
29
ClN
2
O
|
Melting Point
|
249-251ºC
|
MSDS
|
N/A
|
Flash Point
|
209.9ºC
|
Product Description
Chemical Name
|
Bupivacaine Hydrochloride
|
CAS No.
|
14252-80-3
|
Molecular Formula
|
C18H29ClN2O
|
Molecular Weight
|
324.88900
|
PSA
|
32.34000
|
LogP
|
4.70940
|
Appearance&Physical State
|
white solid
|
Boiling Point
|
423.4ºC at 760 mmHg
|
Melting Point
|
249-251ºC
|
Flash Point
|
209.9ºC
|
Vapor Pressure
|
2.24E-07mmHg at 25°C
|
Molecular Weight
|
324.89
|
Purity
|
99.99%
|
Density
|
N/A
|
Boiling Point
|
423.4ºC at 760 mmHg
|
Shelf Life
|
2 Years
|
MOQ
|
1 kg
|
Detailed Photos
Bupivacaine hydrochloride is a long-acting local anesthetic of the amide type, its anesthesia time is 2 to 3 times longer than that of idocaine hydrochloride, and its dispersion is similar to that of idocaine hydrochloride. The Chemicalbook has little effect on circulation and breathing. It is non-irritating to tissues and does not produce methemoglobinemia. Common dosages have no effect on cardiovascular function. Large dosages can cause blood pressure to drop and heart rate to slow down. No obvious rapid tolerability.
Bupivacaine Hydrochloride is available in sterile isotonic solutions with and without (as bitartrate) 1:200,000 for injection via local infiltration, peripheral nerve block, and caudal and lumbar epidural blocks. Solutions of Bupivacaine Hydrochloride may be autoclaved if they do not contain Solutions are clear and colorless.
Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue of mepivacaine and is chemically related to idocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino, . They differ in this respect from the procaine-type local anesthetics, which have an ester linkage.
Bupivacaine hydrochloride (Marcaine, Sensorcaine) has particularly long action, and some nerve blocks last more than 24 hours; this is often an advantage for postoperative analgesia. Its use for epidural anesthesia in obstetrics has attracted interest because it can relieve the pain of labor at concentrations as low as 0.125% while permitting some motor activity of abdominal muscles to aid in expelling the fetus. The lower concentration minimizes the possibility of cardiac toxicity. Fetal drug concentrations remain low, and drug-induced neurobehavioral changes are not observed in the newborn. Bupivacaine also is approved for spinal anesthesia and is approximately four times more potent and more toxic than mepivacaine and ldocaine. It can be used with or without epinephrin.
Proparacaine hydrochloride and etracain are also indicated to produce local anesthesia prior tosurgical procedures such as cataract extraction and pterygium excision, usually as an adjunct tolocally injected anesthetics. Ophthalmic solutions used for intraocular procedures should be
preservative-free.Preservatives may cause damage to the corneal epithelium if a significant quantity of solutionenters the eye through the incision.
Bupivacaine Hcl uses:
Uses antineoplastic
Uses Sodium channel blocker, local anesthetic
Uses Bupivacaine Hydrochloride is the salt form of Bupivacaine (B689561); is a sodium channel blocker, local anesthetic.
Packaging & Shipping
Usually within 3-5 working days after full payment
Shipping by EMS,DHL, UPS ,FEDEX, BY AIR, BY SEA
DHL Express, FedEx and EMS for quantity less than 50KG, usually called as DDU service
Sea shipping for quantity over 500KG; And air shipping is available for 50KG above;
For high value products, please select air shipping and DHL express for safe;50KG, usually called as DDU service
Company Profile
FAQ
Q1: How to confirm the Product Quality before placing orders?
A: By sending you our available samples. Or if you have special requirement on the goods, we can prepare samples according to your requirement and send to you for your confirmation.
Q2: Can you supply free samples?
A: Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can either pay us the shipping cost or arrange a courier to collect the samples.
Q3: What's the MOQ?
A: The minimum order quantity for most of our products is 1kg.
Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price.
Q5: How to place order and make payment?
A: You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation., then you can make payment accordingly.
Q6: How do you treat quality complaint?
A: All our products are strictly tested by our QC, and confirmed by QA; unqualified material will not be released to customer. In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.