Manufacturer Supply High Quality CAS 434-16-2 7-Dehydrocholesterol

Model NO.
TY-02AL
Colour
White
Assay
99%
Shelf
2 Years
Place
China
Package
Foil Bag
Transport Package
25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
Please contact us for quote
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Product Description

Manufacturer Supply High Quality CAS 434-16-2 7-Dehydrocholesterol
Manufacturer Supply High Quality CAS 434-16-2 7-Dehydrocholesterol

Manufacturer Supply High Quality CAS 434-16-2 7-Dehydrocholesterol
 
Product name 7-Dehydrocholesterol
CAS 434-16-2
Appearance white powder
Assay 99%
Storage Cool and Protect from light


Manufacturer Supply High Quality CAS 434-16-2 7-Dehydrocholesterol
7-Dehydrocholesterol
Product Name 7-Dehydrocholesterol

CAS 434-16-2

MF C27H44O

MW 384.64

EINECS 207-100-5

MOL File 434-16-2.mol

Chemical Properties

Melting point 148-152 °C(lit.)
alpha  -116 º (C=1, CHCL3)
Boiling point 451.27°C (rough estimate)
Density  0.9717 (rough estimate)
refractive index  1.5100 (estimate)
storage temp.  -20°C
pka 14.91±0.70(Predicted)
optical activity [α]20/D -115±8°, c = 1% in chloroforrm
Water Solubility  Insoluble
Merck  13,2887
BRN  2224615
InChIKey UCTLRSWJYQTBFZ-DDPQNLDTSA-N
CAS DataBase Reference 434-16-2(CAS DataBase Reference)

EPA Substance Registry System Cholesta-5,7-dien-3-ol, (3.beta.)- (434-16-2)


Manufacturer Supply High Quality CAS 434-16-2 7-Dehydrocholesterol
Usage And Synthesis
Description

7-dehydro Cholesterol (7-DHC) is an immediate precursor of cholesterol. It is reduced to cholesterol by the enzyme 3β-hydroxysterol-Δ7-reductase (DHCR7) in the last step of cholesterol biosynthesis. 7-DHC accumulates in Smith-Lemli-Opitz syndrome (SLOS), a disorder characterized by a mutation in the DHCR7 gene and decreased cholesterol levels in bodily tissues and fluids, as well as microcephaly, intellectual disability, and distinctive dysmorphic features. It is highly susceptible to free radical oxidation, giving rise to several oxysterols that may be involved in the pathogenesis of SLOS. 7-DHC levels are increased in brain, liver, and serum in a rat model of SLOS induced by the DHCR7 inhibitor AY 9944 (Item No. 14611). 7-DHC is a provitamin that is converted to vitamin D3 (Item No. 11792) by ultraviolet-B (UVB) light in a human skin equivalent system and in isolated human skin samples.

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.

Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
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high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
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Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.

Manufacturer Supply High Quality CAS 434-16-2 7-Dehydrocholesterol Manufacturer Supply High Quality CAS 434-16-2 7-Dehydrocholesterol Manufacturer Supply High Quality CAS 434-16-2 7-Dehydrocholesterol Manufacturer Supply High Quality CAS 434-16-2 7-Dehydrocholesterol

 

Organic Intermediate