High Quality API Tolvaptan CAS 150683-30-0 Use for Heart Failure

Colour
White
Transport Package
1kg/Aluminum Bag or 25kg/Drum
Specification
99% min
Trademark
Puya
Origin
China
Production Capacity
5000kilogram/Month
Reference Price
$ 45.00 - 180.00

Product Description

High Quality API Tolvaptan Cas 150683-30-0 Use For Heart Failure

Product Name:    Tolvaptan
Synonyms:    N-[4-(9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide;Tolvaptan;N-[4-[(5R)-7-Chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]-3-methylphenyl]-2-methylbenzamide;N-(4-{[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl}-3-Methylphenyl)-2-MethylbenzaMide;OPC 41061;OPC-41061;SaMsca;Tolvaptan Tablets
CAS:    150683-30-0
MF:    C26H25ClN2O3
MW:    448.94
EINECS:    691-537-5
Product Categories:    Inhibitors;Samsca;APIs;Aromatics;Tolvaptan;Other APIs;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labelled Compounds
Mol File:    150683-30-0.mol


Tolvaptan was developed by Otsuka Corporation of Japan and approved by the FDA in 2009 for the treatment of patients with heart failure and other conditions. The trade name of tolvaptan tablets is Sumycarb, and the difficulty of its synthetic route is mainly reflected in the construction of the benzoheptadecane ring. The treatment of heart failure is a hot topic of research, and the development of new diuretics is one of its strategic goals. So antagonizing arginine pressin is a proven way to prevent the development of heart failure.


Tolvaptan Cas 150683-30-0 of Chemical Properties
Melting point     219-222°C
Boiling point     594.4±50.0 °C(Predicted)
density     1.311±0.06 g/cm3(Predicted)
storage temp.     2-8°C
solubility     DMSO: ≥15mg/mL
pka    13.00±0.70(Predicted)
form     powder
color     white to tan
InChIKey    GYHCTFXIZSNGJT-UHFFFAOYSA-N


Function and Application of Tolvaptan Cas 150683-30-0

1. Tolvaptan (OPC-41061) is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation. Tolvaptan (OPC-41061) is used to treat hyponatremia (low blood sodium levels) assoc
2. It is a selective, competitive arginine vasopressin V2 receptor antagonist f inappropriate antidiuretic hormone (SIADH).
3. Tolvaptan, also known as OPC-41061, is a selective, competitive arginine vasopressin receptor 2 antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure.



Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.
Shipping Terms
By Express By Air By Sea
Suitable for under 50kg
Fast:3-4 days
High cost
Door to door service
Easy to pick up the goods
Suitable for more than 50kg
Fast:3-4 days
High cost
Airport to airport
Professional broker needed
Suitable for more than 500kg
Slow:15-30 days
Low cost
Port to port
Professional broker needed

High Quality API Tolvaptan CAS 150683-30-0 Use for Heart Failure
 

High Quality API Tolvaptan CAS 150683-30-0 Use for Heart Failure
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.

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