Bis(2-chloroethyl)amine hydrochloride Chemical Properties |
Melting point | 212-214 °C(lit.) |
storage temp. | Store below +30°C. |
solubility | >100g/l |
form | Crystalline Powder |
color | White to beige |
Water Solubility | SOLUBLE |
Sensitive | Hygroscopic |
BRN | 3550356 |
CAS DataBase Reference | 821-48-7(CAS DataBase Reference) |
NIST Chemistry Reference | 2,2'-Dichlorodiethylamine hydrochloride(821-48-7) |
EPA Substance Registry System | Ethanamine, 2-chloro-N-(2-chloroethyl)-, hydrochloride (821-48-7) |
Safety Information |
Hazard Codes | Xi,T,C |
Risk Statements | 36/37/38-36-34 |
Safety Statements | 26-45-36/37/39-27 |
RIDADR | 2811 |
WGK Germany | 3 |
RTECS | IA1225000 |
Hazard Note | Irritant/Toxic |
TSCA | Yes |
HazardClass | 8 |
PackingGroup | III |
HS Code | 29211980 |
Toxicity | LD50 orally in Rabbit: 1150 mg/kg |
Bis(2-chloroethyl)amine hydrochloride Usage And Synthesis |
Chemical Properties | white to beige crystalline powder |
Uses | A cytotoxic metabolite of Cyclophosphamide; a deuterated analog of Nor-nitrogen mustard. |
Safety Profile | A poison by inhalation,intraperitoneal, intramuscular, and subcutaneous routes.An experimental teratogen. Human mutation datareported. When heated to decomposition it emits toxicfumes of NH3, NOx, and Cl-. |
Purification Methods | Crystallise the salt from Me2CO or MeOH/Et2O. The picrate has m 112-113o (from EtOH or Me2CO). [Mann J Chem Soc 464 1934, Ward J Am Chem Soc 57 915 1935, |