(S) - (+) -2-Amino-3-Methyl-1-Butanol; CAS 2026-48-4

Colour
White to Light Yellow
Samples
Available
Purity
99%
Certificates
ISO9001/SGS
Package
1kg/5kg/10kg/25kg
Stocks
in Stock
Lead Time
5-7 Working Days
Shelf Life
2-3 Years
Site Audit
Available
Transport
Air/Express/Sea
MOQ
10g
Transport Package
Drum/Bottle/Bags
Trademark
Yunbang
Origin
China
Reference Price
Please contact us for quote
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Product Description

(S)-(+)-2-Amino-3-methyl-1-butanol;CAS 2026-48-4

(S) - (+) -2-Amino-3-Methyl-1-Butanol; CAS 2026-48-4
 
 
(S)-(+)-2-Amino-3-methyl-1-butanol Chemical Properties
Melting point  30-34 °C
alpha  16 º (c=10,EtOH)
Boiling point  81 °C8 mm Hg(lit.)
density  0.926 g/mL at 25 °C(lit.)
refractive index  n 20/D 1.4548(lit.)
Fp  196 °F
storage temp.  Store at +2°C to +8°C.
form  Liquid After Melting
pka 12.82±0.10(Predicted)
color  Clear slightly yellow
optical activity [α]25/D +10°, c = 10 in H2O
Water Solubility  Soluble in water.
Sensitive  Air Sensitive
BRN  1719137
InChIKey NWYYWIJOWOLJNR-RXMQYKEDSA-N
CAS DataBase Reference 2026-48-4(CAS DataBase Reference)
NIST Chemistry Reference (S)-(+)-2-Amino-3-methyl-1-butanol(2026-48-4)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36-36/37/38
Safety Statements  26-24/25-36
WGK Germany  3
F  10-23
HazardClass  IRRITANT
HS Code  29221980
 
(S)-(+)-2-Amino-3-methyl-1-butanol Usage And Synthesis
Chemical Properties white to light yellow crystal powde
Uses L-Valinol is used as a reagent in the synthesis of simple 1,3-thiazolidine-2-thione derivatives which can exhibit fungicidal activity. L-Valinol is also used as a reagent in the synthesis of small-molecule inhibitors of MDM2-p53 protein-protein interaction (MDM2 inhibitors) in clinical trials for the treatment of cancer.
Purification Methods Purify S-valinol by vacuum distillation using a short Vigreux column (p 11). Alternatively it is purified by steam distillation. The steam distillate is acidified with HCl; the aqueous layer is collected and evaporated. The residue is dissolved in butan-1-ol, filtered and dry Et2O added to crystallise the hydrochloride salt (hygroscopic), m 113o. The free base can be obtained by suspending the salt in Et2O and adding small volumes of saturated aqueous K2CO3 until effervescence is complete and the mixture is distinctly alkaline. At this stage the aqueous layer should appear as a white sludge. The mixture is heated to boiling and refluxed for 30minutes (more Et2O is added if necessary). Purification of Biochemicals - Amino Acids and Peptides The Et2O layer is decanted off from the white sludge, the sludge is extracted twice with Et2O (by boiling for a few minutes), the combined organic layers are dried (KOH pellets), evaporated and the residue is distilled in a vacuum. [Nagao et al. J Org Chem 55 1148 1990, Beilstein 4 III 805.]
 
(S) - (+) -2-Amino-3-Methyl-1-Butanol; CAS 2026-48-4
(S) - (+) -2-Amino-3-Methyl-1-Butanol; CAS 2026-48-4 (S) - (+) -2-Amino-3-Methyl-1-Butanol; CAS 2026-48-4 (S) - (+) -2-Amino-3-Methyl-1-Butanol; CAS 2026-48-4
Company Informations:

Hunan Yunbang Pharmaceutical Co., Ltd. ( Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".

We can provide customers with customized processing, research and development services;
We can develop high-end Pharmaceutical and chemical products with high technical difficulties,high barriers and unique production processes;
We can provide 100 grams Grade, kilograms, and hundred kilograms of raw material pharmaceutical intermediates and other products.
We can perform -100°C to 300°C reaction.

R&D strength is the company's core competitiveness.Yunbangpharm has maintains a good cooperation relationship with many Universities and Research institutes locally, which can quickly transform R&D results into industrial production.

Our goal : To achieve the integrated upgrade of P harmaceutical intermediates, raw materials and high-end chemical products, adhere to "serving pharmaceutical companies, creating our brands" to provide customers with high-quality and low-cost pharmaceutical and chemical products, realizing Win-win cooperation and common development.

 

Organic Intermediate