Local Anesthetic Drugs Pain Killer Chemicals Bupivacaine CAS 2180-92-9 Powder

Model NO.
2180-92-9
Colour
White
Water Solubility
101.5mg/L(25 ºC)
Exact Mass
288.220154
Pka
8.09; Also Reported as 8.17(at 25ºC)
Refractive Index
1.5700 (Estimate)
Psa
32.34000
Logp
3.64
Storage Temp.
2-8°c
Vapour Pressure
0.0±0.8 Mmhg at 25°c
Molecular Formula
C18h28n2o
Density
1.0±0.1 g/cm3
Flash Point
209.9±28.7 °c
Melting Point
N/a
Molecular Weight
288.428
Boiling Point
423.4±45.0 °c at 760 Mmhg
CAS
721-50-6
Transport Package
Packing Within 3 Working Days
Specification
25kg/Cardboard barrel
Trademark
Wuhan Mulei
Origin
Hebei
HS Code
2924299090
Production Capacity
500000kg
Reference Price
$ 14.58 - 16.20
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Product Description

Product Description

Bupivacaine

 
 
Bupivacaine structure
Local Anesthetic Drugs Pain Killer Chemicals Bupivacaine CAS 2180-92-9 Powder
Common Name Bupivacaine
CAS Number 2180-92-9 Molecular Weight 288.428
Density 1.0±0.1 g/cm3 Boiling Point 423.4±45.0 °C at 760 mmHg
Molecular Formula C 18 H 28 N 2 O Melting Point N/A
MSDS N/A Flash Point 209.9±28.7 °C


Product Description

 
Product Name: Bupivacaine
Synonyms: MARCAINE;BUPIVACAINE;BUPIVACAINE BASE;
CAS: 2180-92-9
MF: C18H28N2O
MW: 288.43
EINECS: 218-553-3
Product Categories: research chemical;
Mol File: 2180-92-9.mol
 

Bupivacaine Descriptions:
Bupivacaine was synthesized simultaneously with mepivacainein 1957 but was at first overlooked because of the increasedtoxicity compared with mepivacaine. When themethyl on the cyclic amine of mepivacaine is exchanged fora butyl group the lipophilicity, potency and the duration ofaction all increase. Literature reports of cardiovascular toxicity,including severe hypotension and bradycardia, areabundant in the literature.91 Bupivacaine is highly bound toplasma proteins (95%), and thus the free concentration mayremain low until all of the protein binding sites are occupied.After that point, the plasma levels of bupivacaine rise rapidlyand patients may progress to overt cardiac toxicity withoutever showing signs of CNS toxicity. The cardiotoxicity ofbupivacaine is a result of its affinity to cardiac tissues and itsability to depress electrical conduction and predispose theheart to reentry types of arrhythmias. The cardiotoxicity ofbupivacaine was found to be significantly more prominentwith the "R" isomer, or the racemic mixture, thus the "S"stereoisomer is now on the market as levobupivacaine.

Mechanism of action    Bupivacaine is a local anaesthetic containing a chiral centre and adopts dextro and laevo forms. The enantiopure l form is less cardio- and neurotoxic and has an equivalent potency to the racemic mixture; therefore levobupivacaine is often preferred to reduce the potential for toxicity. Stereoselectivity describes the differences in response at a given receptor for the different enantiomers (such as the response discussed for S(+) ketamin). The opioid and NMDA receptors also exhibit stereoselectivity.

Bupivacaine uses: 

Bupivacaine is an anesthetic (numbing medicine) that is used as a local (in only one area) anesthetic.

Bupivacaine is given as an epidural injection into the spinal column to produce numbness during labor, surgery, or certain medical procedures.

Bupivacaine is also used as an anesthetic for dental procedures.

Uses    Like lidocaine and mepivacaine, bupivacaine is used in infiltration, spinal, and epidural anesthesia in blocking nerve transmission. Its most distinctive property is its long-lasting action. It is used for surgical intervention in urology and in lower thoracic surgery from 3 to 5 h in length, and in abdominal surgery lasting from 45 to 60 min. It is used to block the trifacial nerve, the sacral and brachial plexuses, in resetting dislocations, in epidural anesthesia, and during Cesarian sections.
Uses    Anesthetic (local).

 
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Detailed Photos


Local Anesthetic Drugs Pain Killer Chemicals Bupivacaine CAS 2180-92-9 Powder Local Anesthetic Drugs Pain Killer Chemicals Bupivacaine CAS 2180-92-9 Powder

 

Product Parameters

 
Product Information

Chemical & Physical Properties
Density 1.0±0.1 g/cm3
Boiling Point 423.4±45.0 °C at 760 mmHg
Molecular Formula C 18 H 28 N 2 O
Molecular Weight 288.428
Flash Point 209.9±28.7 °C
Exact Mass 288.220154
PSA 32.34000
LogP 3.64
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.547

 

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We can offer different standard Procaine HCL for you such as
USP/BP/ISO 9001/GMP.
Also  We guarantee that our products will be delivered to you in time.
Last but no least, we   aimto   exceed   expectations  through  consistently   providing   quality  and  value  in our  products   and   services

 
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Support sample ! MOQ 1kg fast delivery
1-24kg ` Aluminium foil bags
Over 25kg ` 25kg bags or 25 kg drums
 
 
Storage: 

1. Stored in a clean, cool and dry area; keep away from strong, direct light.

2. Shelf Life is 2 years when properly stored.

 

Packing: 
1. Inner double plastic bags----25kg/Fiber drum (36*36*45cm, GW: 28kg, NW: 25kg);

2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).

3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).


P.S.: we accept packaging customization.

 

Delivery:   

1. In stock products are normally shipping within 3 working days.

2. For rush delivery, please contact our sales team for particular arrangement

 

Shipping:

1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.

2. Shipping details & shipping documents will be provided and sent by email.

3. We keep tracking the shippment until clients well received.

4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.

Local Anesthetic Drugs Pain Killer Chemicals Bupivacaine CAS 2180-92-9 Powder Local Anesthetic Drugs Pain Killer Chemicals Bupivacaine CAS 2180-92-9 Powder Local Anesthetic Drugs Pain Killer Chemicals Bupivacaine CAS 2180-92-9 Powder Local Anesthetic Drugs Pain Killer Chemicals Bupivacaine CAS 2180-92-9 Powder

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Local Anesthetic Drugs Pain Killer Chemicals Bupivacaine CAS 2180-92-9 Powder

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Local Anesthetic Drugs Pain Killer Chemicals Bupivacaine CAS 2180-92-9 Powder

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WHY CHOOSE US
MU LEI (Wuhan) is committed to helping clients reach their goals, to providing high quality products and efficient shipments.

Our strong sense of responsibility with client projects means that we are constantly striving to provide solutions, even for issues they aren't yet aware of.

This sense of responsibility also means we value and promote seamless interaction with clients, and ensure the best value is obtained from their research budget.

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Local Anesthetic Drugs Pain Killer Chemicals Bupivacaine CAS 2180-92-9 Powder

FAQ

In this page, we will continue to update frequently asked questions and answers about the crystaline, Benzocaine powder, Lidocaine hcl powder, Procaine hcl crystal, fluffy Lidocaine, tetracaine chemical, crystaline tetramisole hydrochloride, cas  and so on, Stay tuned....

  • Q What's your advantage?

    A

    The series of natural extracted product are all self-developed, produced and tested. Mature production technology, strict quality management system and cost control system, ensure the product stability and competitive price.

  • Q How to deal with quality complaints or the goods get loss?

    A

    Firstly, every batch of our product was tested by authorized independent third party, Analysis testing center, Shanghai branch, Chinese Academy of Science. We send goods to customers with test report and COA (or depends on customers' request). 


    If it is our product quality issue or due to the force majeures, we will send you another shipment for free.
     

  • Q Is there any discount?

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  • Q How to place an order?

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  • Q Can I get some samples?

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