Product Name: Sodium 2-propylpentanoate
Synonyms: 2-propyl-pentanoicacisodiumsalt;sodiumalpha,alpha-dipropylacetate;sodiumbispropylacetate;sodiumn-dipropylacetate;valerin;2-PROPYLPENTANOIC ACID NA;2-PROPYLPENTANOIC ACID SODIUM SALT;SODIUM DIPROPYLACETATE
CAS: 1069-66-5
MF: C8H15NaO2
MW: 166.19
EINECS: 213-961-8
Melting point: 300 °C
Storage temp.: Desiccate at RT
Description:
(a) Di-n-propyl cyanacetic acid First of all, a sodium n-propylate solution was prepared from 7.42 g (0.322 mol) of sodium and 180 ml of anhydrous, by heating with gentle reflux until complete dissolution of the sodium.
Into a 500 ml spherical flask, equipped with a dropping funnel, a mechanical stirrer, a thermometer and a condenser, above which was disposed a calcium chloride trap, were introduced 16.95 g (0.141 mol) of ethyl cyanacetate and 40.69 g (0.33 mol). This mixture was heated to 45°C and then there was added thereto, slowly and while stirring, the previously prepared solution of sodium n-propylate, keeping the temperature of the reaction medium at 50°-55°C by gentle external cooling.With the completion of the operation of introduction, the mixture was brought to reflux temperature in 30 minutes and kept at this temperature for 3 hours. The was then distilled and the distillation stopped when the temperature of the residual mass had reached 115°C.
Usage:
Antiepileptic; increases levels of GABA in the brain
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