Description:
L-Carnosine is a dipeptide composed of β-alanine and L-histidine that has been found in rat olfactory bulb, skeletal muscle, brain, kidney, and spleen tissues, as well as human skeletal muscle, and has diverse biological activities. It is a metal chelator that forms complexes with copper, cobalt, nickel, cadm1ium, or zinc. Dietary administration of L-carnosine (60 mg/kg per day) reduces plasma levels of advanced glycation end products (AGEs) in diabetic rats. It reduces brain edema, blood-brain barrier disruption, microglial activation, and neuronal apoptosis in a rat model of intracerebral hemorrhage when administered at a dose of 1,000 mg/kg. L-Carnosine (250, 500, and 1,000 mg/kg, i.p.) reduces hepatic protein carbonylation and necrosis in a rat model of cirrhosis induced by bile duct ligation. It also reduces lung myeloperoxidase (MPO) activity, production of reactive oxygen species (ROS), and TNF-α and IL-6 levels, as well as alveolar hemorrhage, interstitial edema, and pulmonary leukocyte infiltration in a mouse model of LPS-induced lung injury.
Uses
: L-Carnosine is a naturally-occurring histidine-containing compound and the biological role of this dipeptide is to act as cytosolic buffering agents. Other roles ascribed to L-Carnosine include action s as neurotransmitters, modulation of enzymic activities and chelation of heavy metals. Studies indicate an ability to boost the immunological functions. In cosmetics, it has anti-aging and skin-conditioning applications.
Product Name
|
L-Carnosine
|
CAS No.
|
305-84-0
|
Colour
|
White
|
Density
|
1.2673 (rough estimate)
|
Storage temp.
|
-20°C
|
Pka
|
2.62
|
Boiling Point
|
1071.6±65.0 °C(Predicted)
|
Water Solubility
|
DMSO (Very Slightly), Water (Slightly)
|
Form
|
crystalline
|
Mol File
|
305-84-0.mol
|
Wuhan Hansheng New Material Technology Co. Ltd
is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.
We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on
1.Cooperate with research institutions, we strictly control the process from raw material to finished product.
2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.
3.We can send the goods to your delivery address directly. It is relatively safe and fast.
4.Quick and clear response to customers questions.
5.We could make our price discount if you place a substantial order with us.
6.Products can be packaged according to customer requirements.
1. Are you a trade company or factory?
We are a factory with our own trading company.
2. How do you control the quality?
Our factory is equipped with professional technicians to inspect the quality around production lines. The inspection test would be made every 2 hours to ensure the production conform to quality standard. We also accept BV, SGS, or any third pary inspection.
3. How long is lead time?
We deliver goods within
3 days for
small order,
7-10 days
for bulk order.
4. Where is your factory located? How can I visit the factory?
Our factory is located in
Hebei, China
5. Can I get some samples?
Yes.
6. How to start orders or make payments?
Proforma Invoice will be issued first after confirmation of order, enclosed our bank information. Payment could be done by
T/T or Western Union
.
7. How to confirm the product quality before placing order?
You can
get samples
of all products for test before placing order .
8. How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.