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High Quality Domperidone CAS 57808 -66-9 for Gastrointestinal Motivation

Model NO.
PY202310201659
Colour
Yellow
Transport Package
1kg/Aluminum Bag or 25kg/Drum
Specification
99% min
Trademark
Puya
Origin
China
Production Capacity
5000kilogram/Month
Reference Price
$ 45.00 - 450.00
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Product Description

High Quality Domperidone CAS 57808-66-9 For Gastrointestinal Motivation

Product Name:    Domperidone
Synonyms:    kw-5338;midazol-1-yl)propyl)-4-piperidinyl)-;Domperidone,Motilium;5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one;5-Chloro-1-[1-[3-(2-oxo-1-benzimidazolyl)propyl]-4-piperidyl]benzimidazol-2-one;DoMperidone-d6;DoMperidone Sustained Release Pellets;DOMPERIDONE BASE
CAS:    57808-66-9
MF:    C22H24ClN5O2
MW:    425.91
EINECS:    260-968-7
Product Categories:    VIOXX;Other APIs;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Dopamine receptor;Isotope Labelled Compounds
Mol File:    57808-66-9.mol

Domperidone, a benzimidazole derivative, is a peripheral dopamine receptor antagonist that acts directly on dopamine receptors in the gastrointestinal wall to increase lower esophageal sphincter tone, prevent gastro-esophageal reflux, enhance gastric motility, promote gastric emptying, coordinate gastric and duodenal motility, inhibit nausea and vomiting, and effectively prevent bile reflux without affecting gastric juice secretion.


Domperidone CAS 57808-66-9  of Chemical Properties
Melting point     240-244°C
density     1.2904 (rough estimate)
refractive index     1.5400 (estimate)
storage temp.     Store at RT
solubility     DMSO: >10 mg/mL
form     solid
pka    pKa 7.90 (Uncertain)
color     white
Water Solubility     Slightly soluble in water.
Merck     14,3418
Stability:    Stable. Incompatible with strong oxidizing agents.
InChIKey    FGXWKSZFVQUSTL-UHFFFAOYSA-N
CAS DataBase Reference    57808-66-9(CAS DataBase Reference)

Function and Application of Domperidone CAS 57808-66-9
1. Domperidone is a benzimidazole compound with strong pro-gastric motility and antiemetic effects, which can strengthen the tone of lower esophageal sphincter, prevent gastro-esophageal reflux, enhance gastric peristalsis, promote gastric emptying, coordinate gastric and duodenal motility, inhibit nausea and vomiting, and effectively prevent bile reflux without affecting gastric juice secretion. It is a peripheral dopamine receptor antagonist, which directly blocks the dopamine receptors in the stomach and intestines and presents a pro-gastric motility effect. It enhances the peristalsis of the esophagus and the tone of the lower esophageal sphincter. Because of its poor penetration of the blood-brain barrier, it has little antagonistic effect on dopamine receptors in the brain, thus excluding psychiatric and central nervous side effects.
2. Domperidone is a commonly used gastric stimulant and antiemetic.


Packing And Shipping
1.Preferentially DHL, FedEX or TNT for quantity less than 50kg, air shipping for 100kg above, sea shipping for quantity over 500kg.
2.For customers from Russia,Mexico,Turkey,Solvenia,Romania,etc,before placing an order,please kindly confirm if you can make clearance when goods reach your customs.
Shipping Terms
By Express By Air By Sea
Suitable for under 50kg
Fast:3-4 days
High cost
Door to door service
Easy to pick up the goods 		Suitable for more than 50kg
Fast:3-4 days
High cost
Airport to airport
Professional broker needed 		Suitable for more than 500kg
Slow:15-30 days
Low cost
Port to port
Professional broker needed

High Quality Domperidone CAS 57808-66-9 for Gastrointestinal Motivation
 

High Quality Domperidone CAS 57808-66-9 for Gastrointestinal Motivation
Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.

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