Applications:
Sodium Triacetoxyborohydride is a hydride reagent used in stereoselective reductive amination.
1.Sodium Triacetoxyborohydride(STAB) is a hydride reagent used in stereoselective reductive amination.
It is able to replace toxic sodium cyanoborohydride under most conditions. It is selective in reducing aldehydes to alcohols in the presence of ketones. STAB is also stable in anhydrous acids, which enables reductive amination of aldehydes and ketones. It used in reductive amination of ketones and aldehydes and reductive amination/lactamization of carbonyl compounds with amines.
2.Reagent for the reductive amination of aryl aldehydes.The advantage of STAB compared to sodium cyanoborohydride is evident. STAB, being non-toxic, is easier to handle and forms no toxic by-products, making the treatment of process waste after the reaction simple and less costly.
3.Selective reducing agent in organic synthesis.
4.Sodium triacetoxyborohydride is especially suitable for reductive aminations. Since the reaction rate for the reduction of iminium ions is much faster than for ketones or even aldehydes, the reductive amination can be carried out as a one-pot procedure by introducing the reducing agent into a mixture of the amine and carbonyl compound. The presence of a stoichiometric amount of acetic acid, which catalyzes the imine formation and provides the iminium ion, doesn't present any problem under these conditions.
Product Name: | Sodium triacetoxyborohydride |
Synonyms: |
stab
;
SODIUM TRIACETOXYBOROHYDRIDE
;
SODIUM TRIACETOXYHYDROBORATE
;
sodiumtriacetoxyborohydride,
calselectstab ; Sodium Triacetoxyborohyride ; Sodium triacetoborohydride ; Sodium triacetohydroborate, Triacetohydroborate sodium salt ; Sodiumtriacetoxyborohydride,95% |
CAS: | 56553-60-7 |
MF: | C6H10BNaO6 |
MW: | 211.94 |
EINECS: | 411-950-4 |
Product Categories: |
oron compounds
;
Selectivity reducing agent
;
B (Classes of Boron Compounds)
;
Classes of Metal Compounds
;
Na (Sodium) Compounds (excluding simple sodium salts)
;
organic intermediates
;
Reduction
;
Synthetic Organic Chemistry ; Tetrahydroborates ; Typical Metal Compounds ; Borohydrides ; Synthetic Reagents ; metal hydride ; 56553-60-7 |
Mol File: | 56553-60-7 .mol |
Items
|
Specifications
|
Appearance
|
White solid
|
Purity
|
≥99%
|
Loss on drying
|
≤0.3%
|
Residue on ignition
|
≤0.1%
|
Heavy metals
|
≤0.05%
|
Packing
Liquid:
Iron drum & plastic drum packaging
25kg
/drum
170kg per unit
IBC/ISO tank
Solid
Plastic bag & kraft paper bag & fiber drum
1kg per bag
25kg per bag/drum
1-10 kgs packaging aluminum foil bag inside and carton box outside.
25kgs packaging fiber drum outside and plastic bag inside.
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