High Quality Idelalisib / CAL-101 CAS 870281-82-6 For Small lymphocytic lymphoma 

Product Name:    CAL-101
Synonyms:    CAL101,CAL-101;CAL-101;GS1101;CAL-101 (GS-1101);5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]-4(3H)-quinazolinone;CAL-101 (Idelalisib, GS-1101);(S)-2-(1-((9H-Purin-6-yl)aMino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;Idelalisib(CAL-101)
CAS:    870281-82-6
MF:    C22H18FN7O
MW:    415.42
EINECS:    807-438-9
Product Categories:    Akt;mTOR;Inhibitors;PI3K;API;API;Inhibitor
Mol File:    870281-82-6.mol

Idelalisib (CAS 870281-82-6) is a potent (IC50 = 2.5nM) and selective (IC50's: PI3Ka = 820nM, PI3Kb = 565nM, PI3Kg = 89nM) PI3Kd inhibitor.1,2 Useful clinical agent for the treatment of various blood cancers. Idelalisib attenuates regulatory T cells (Treg) but not conventional T cells (Tconv) resulting in a significant increase in tumor-infiltrating antigen-specific CD8 T cells in a murine lung cancer model.3 Conversely, systemic PI3Kd inactivation antagonized anti-CTLA-4 and anti-PD-L1 treatment.4 Others have found that Idelalisib minimally influenced rituximab- and obinutuzumab-mediated Ab-dependent cellular cytotoxicity in human lymphoma cells.5

Idelalisib / CAL-101 CAS 870281-82-6  of Chemical Properties
Melting point     250-252oC
Boiling point     733.4±70.0 °C(Predicted)
density     1.47
storage temp.     -20°C
solubility     Soluble in DMSO (>25 mg/ml)
form     White solid.
pka    10.00±0.10(Predicted)
color     White
Stability:    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Function and Application of  Idelalisib / CAL-101 CAS 870281-82-6

Company Profile
Anhui puya biological technology co.,ltd was established in Hefei. Registered capital is 5 million. It is specialized in manufacture plant extract, API and chemicals raw material powder, food additives and oil. which are applied to skin care, healthcare, weight loss products, sex improvement, and pharmaceuticals. We will uphold honesty and pragmatic, innovative and enterprising service purposes, and provide a variety of quality services to our customers at abroad. It aims at supplying good product and comfort service. The strict quality control is to meet the customer's requirement, to get a highly praised and to be high quality supplier. If you have any question, or need samples, please feel free to contact us.

FAQ
Q1. What's the MOQ?
A: Usually 1 kg.  It is based on the different product. Some are 1g and some are 1 ton. Please be free to consult our salesman.
 
Q2. What's the shipping time?
A: If in stock, we will ship it out immediately.  By FedEx will be 3~5 days to you.
 
Q3. If I need less than the MOQ, is it possible?
A: Yes. Please be free to consult our salesman.
 
Q4. Can you supply the free sample?
A: Usually it is possible. but the shipping cost be paid by customers. It based on the different product. Please be free to consult our salesman.
 
Q5. How to store the product?
A: Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.
 
Q6: What's your main payment method?
A: T/T, trade assurance, west union, money gram.
 
Q7: Do you have COA, MSDS, CO, Health certificate, form 9 or other certificate?
A: Yes, we have. pls be free to contact us to get updated one.