6-Chloronicotinic acid Chemical Properties |
Melting point | 190 °C (dec.)(lit.) |
Boiling point | 241.15°C (rough estimate) |
density | 0.5 |
refractive index | 1.5870 (estimate) |
Fp | 192°C |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | deionized water: soluble |
form | Crystalline Powder |
pka | 3.24±0.10(Predicted) |
color | Off-white to beige |
Water Solubility | Soluble in water (2 mg/ml at 20°C), ethanol, meth anol, DMSO, and slightly soluble in chlorof orm. |
Decomposition | 192 ºC |
BRN | 115993 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
InChIKey | UAWMVMPAYRWUFX-UHFFFAOYSA-N |
CAS DataBase Reference | 5326-23-8(CAS DataBase Reference) |
NIST Chemistry Reference | 6-Chloronicotinic acid(5326-23-8) |
EPA Substance Registry System | 6-Chloronicotinic acid (5326-23-8) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-24/25-37/39 |
WGK Germany | 3 |
Hazard Note | Irritant |
TSCA | T |
HazardClass | IRRITANT |
HS Code | 29333999 |
6-Chloronicotinic acid Usage And Synthesis |
Chemical Properties | Off-white to beige crystalline powder |
Uses | 6-Chloronicotinic acid is used as building block for different chemical synthesis. Product Data Sheet |
Uses | 6-Chloropyridine-3-carboxylic acid (6-chloronicotinic acid/6-CNA) has been used to study its photolytic and photocatalytic degradation. The product has been used as a media component during the isolation of 6-CNA degrading bacterial strain from imidacloprid-exposed soil samples. |
General Description |
6-Chloropyridine-3-carboxylic acid is a metabolite of the neonicotinoid pesticides, imidacloprid and acetamiprid and occurs in different environmental matrices.(3) It is widely used in agricultural crop protection, domestic insect control and environmental pest management.
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Purification Methods | Purify it by recrystallisation from hot H2O and sublime it in a vacuum. [Pechmann & Welsch Chem Ber 17 2384 1884, Herz & Murty J Org Chem 26 122 1961, Beilstein 22/2 V 177.] |