Chemical Raw Material Gabapentin CAS 60142-96-3
Product Description
Chemical Raw Material Gabapentin CAS 60142-96-3
Gabapentin is a GABA analog used to treat epilepsy and neuralgia.
Gabapentin is structurally similar to GABA (sc-203053; γ-aminobutyric acid) and is reported in various research studies to increase GABA concentrations within the brain. Gabapentin is also noted to bind to a novel site on voltage-sensitive Ca2+ channels.
Additionally, Gabapentin is reported to demonstrate inhibition of dopamine release from caudate nucleus, preventneuronal cell death, and is antinociceptive.
| Product Name | Gabapentin |
| CAS | 60142-96-3 |
| Appearance | White Powder |
| Molecular formula | C9H17NO2 |
| Molecular Weight | 171.23700 |
| Assay | 99.5% |
| Shelf Life | 24 months when properly stored |
| Storage | Keep in a cool, dry, dark location |
Product Name:Gabapentin
CAS No.: 60142-96-3
Molecular Formula: C9H17NO2
Molecular Weight: 171.23700
Purity : 99.5% HPLC
Elimination half-life time:5-7 hours
Appearance: White powder
Typical use level :100mg
Standard Packing : 100g,1kg,25kg
Shelf Life :2 years
Storage:Room temperature away from light
Use:
1.Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier.
2.Used as an anticonvulsant.antipsychotic, 5HT2A antagonist
3.selective H1-receptor antagonist
4.For the treatment of adult Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN).
5.Gabapentin is an Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.
| ITEM | SPECIFICATION | RESULT | ||||
| Description | White or off-white crystalline powder | White crystalline powder | ||||
| Identification | IR | IR spectrum is consistent with Gabapentin RS | Complies | |||
| HPLC | Conform with the RT of the major peak in HPLC with USP Gabapentin WPS | Complies | ||||
| PH | 6.5~8.0 | 7.4 | ||||
| Water | ≤0.5% | 0.04% | ||||
| Residue on ignition | ≤0.1% | 0.03% | ||||
| Heavy metals | ≤0.002% | <0.002% | ||||
| Residual solvents (Ethanol) | ≤0.50% | 0.01% | ||||
|
Late eluting impurities
-Any individual impurity |
≤0.10% | Not detected | ||||
| Total impurities | ≤0.5% | 0.003% | ||||
| Assay | 98.0%~102.0% | 99.9% | ||||
| Limit of chloride | ≤0.01% | 0.004% | ||||
| Conclusion | The product meet the testing requirements | |||||
Function:
Gabapentin is an anticonvulsant that is chemically unrelated to any other anticonvulsant or mood regulating medication. Gabapentin received final approval for marketing in the USA on 30 December 1993 and is labeled only for use as an anticonvulsant. It is also widely used to treat individuals suffering from many kinds of pain problems, tremors, restless legs syndrome, hot flashes associated with menopause, and various psychiatric disorders.
Application:
Gabapentin can be used for post-herpetic neuralgia; For the adjunctive treatment of partial seizures with or without secondary systemic seizures in adults and children over 12 years of age. It can also be used for the adjuvant treatment of partial seizures in children aged 3 to 12 years.
Gabapentin is an antianxiety drug. It is used for the additional treatment of epilepsy patients with localized seizures which cannot be satisfactorily controlled or tolerated by conventional antiepileptic drugs, and epilepsy patients with localized seizures and subsequent generalized seizures. Anti-anxiety medication.
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