Manufacturer Supply High Quality CAS 8005 -44-5 Isatoic Anhydride

Model NO.
TY-02AL
Colour
White
Package
Foil Bag
Place
China
Assay
99%
Shelf
2 Years
Transport Package
25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
Please contact us for quote
Contact Us

Product Description

Manufacturer Supply High Quality CAS 8005-44-5 Isatoic Anhydride
Manufacturer Supply High Quality CAS 8005-44-5 Isatoic Anhydride

Manufacturer Supply High Quality CAS 8005-44-5 Isatoic Anhydride
 
Product name Isatoic Anhydride
CAS 118-48-9
Appearance white powder
Assay 99%
Storage Cool and Protect from light


Manufacturer Supply High Quality CAS 8005-44-5 Isatoic Anhydride
Isatoic Anhydride
Product Name Isatoic Anhydride

CAS 118-48-9

MF C8H5NO3

MW 163.13

EINECS 204-255-0

MOL File 118-48-9.mol

Chemical Properties

Melting point 233 °C (dec.) (lit.)
Boiling point 290.19°C (rough estimate)
Density  1,52 g/cm3
vapor density  5.6 (vs air)
refractive index  1.5510 (estimate)
Flash point 308 °C
storage temp.  Store below +30°C.
solubility  0.3g/l
pka 11.06±0.20(Predicted)
form  Powder
color  Beige to brown
Water Solubility  decomposes
Sensitive  Moisture Sensitive
BRN  136786
CAS DataBase Reference 118-48-9(CAS DataBase Reference)
NIST Chemistry Reference Isatoic anhydride(118-48-9)
EPA Substance Registry System 2H-3,1-Benzoxazine-2,4(1H)-dione (118-48-9)



Manufacturer Supply High Quality CAS 8005-44-5 Isatoic Anhydride
Usage And Synthesis
Chemical Properties

BEIGE TO BROWN POWDER

Uses

Isatoic anhydride is a potent inactivator of α-chymotrypsin and inactivates stoichiometrically. Isatoic Anhydride is an important compound in the preparation of serine protease inhibitors.

Definition

A bicyclic molecule composed of a benzene ring attached at the oand mpositions to a heterocyclic ring. It forms useful anthraniliic aciid derivatives by reaction with hydrogen.

Preparation

Phosphorus tribromidee (0.035 mol) was added to a solution of N-carbethoxy- or N-carbobenzoxy-anthranilic aciid (0.1 mol;prepared by coupling anthranilic aciid with the corresponding carbalkoxy chloride in the usual way) in anhydrous diethyl etheer (100 mL). After 24 h at room temperature, isatoic anhydride had separated as a microcrystalline product. It was collected by filtration, washed with dry diethyl etheer, and recrystallized from ethanol. Yield ca. 90%.

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.

Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.

Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.

Manufacturer Supply High Quality CAS 8005-44-5 Isatoic Anhydride Manufacturer Supply High Quality CAS 8005-44-5 Isatoic Anhydride Manufacturer Supply High Quality CAS 8005-44-5 Isatoic Anhydride Manufacturer Supply High Quality CAS 8005-44-5 Isatoic Anhydride

 

Organic Intermediate