6-BROMO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE Chemical Properties |
Melting point | 170.0-173.1 °C |
Boiling point | 453.3±45.0 °C(Predicted) |
density | 1.559±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
pka | 14.22±0.20(Predicted) |
Safety Information |
MSDS Information |
6-BROMO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE Usage And Synthesis |
Uses | 6-bromo-3,4-dihydroisoquinolin-1(2H)-one is an intermediate used in the synthesis of benzolactams as dopamine D3 receptor ligands.IT is also used in the synthesis of new, selective 3-aminopyrazole based MK2-inhibitors that was proved to inhibit intracellular phosphorylation of hsp27 as well as LPS-induced TNFα release in cells. |