Detailed Product Information
 
Product Name : NSI-189 Phosphate
Trade Name:  NSA-189
CAS No.:  1270138-41-4
Molecular Formula:   C22H33N4O5P
Molecular Weight:  464.503 g/mol
Purity: 99% HPLC
Appearance:  White Powder
Typical use : A ntidepressants
Standard Packing:  100gram,1kg,25kg
Shelf Life:   2 years
Storage: Room temperature away from light

Description:

NSI-189 is a benzylpiperizine-aminiopyridine, a novel chemical entity that stimulates neurogenesis of human hippocampus-derived neural stem cells   in vitro   and stimulates neurogenesis in murine hippocampus   in vivo . Emerging evidence also indicates that NSI-189 phosphate has regionally specific effects insofar as neurogenesis is observed largely in the subventricular zone of the hippocampus. Results from a preliminary proof of concept study suggests that NSI-189 may be capable of mitigating depressive symptoms and improve cognitive function in adults with DSM-5-defined Major Depressive Disorder (MDD).

NSI-189 is a new investigational antidepressant, which is purported to work differently from existing antidepressants. Researchers suggest this drug may potentially help those who do not respond to conventional medications. Research is also ongoing for its cognitive-enhancing effects. However, NSI-189 failed in a recent clinical trial. Learn about all the research behind this drug.

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