1-METHYL-4-[5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABORALAN-2-YL)PYRIDINE-2-YL]PIPERA ZINE Chemical Properties |
Melting point | 125 °C |
Boiling point | 435.2±45.0 °C(Predicted) |
density | 1.10±0.1 g/cm3(Predicted) |
storage temp. | Inert atmosphere,2-8°C |
pka | 8.41±0.31(Predicted) |
form | solid |
color | white |
Safety Information |
Hazard Codes | C |
Risk Statements | 22-34 |
Safety Statements | 22-26-36/37/39-45 |
TSCA | No |
MSDS Information |
1-METHYL-4-[5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABORALAN-2-YL)PYRIDINE-2-YL]PIPER AZINE Usage And Synthesis |
Uses | 1-Methyl-4-[5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-yl]pip erazine is used to prepare yrazolopyridine and indazoles as histone lysine methyltransferase EZH2 inhibitors. It is also used to synthesize tetrahydropyrido pyrazines as anaplastic lymphoma kinase inhibitors. |