Manufacturer Supply High Quality CAS 633-65-8 Berberine Hydrochloride Berberine HCl

Model NO.
TY-02ALI
Colour
White
Package
Foil Bag
Place
China
Assay
99%
Shelf
2 Years
Transport Package
25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
Please contact us for quote
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Product Description

Manufacturer Supply High Quality CAS 633-65-8 Berberine Hydrochloride Berberine HCl
Manufacturer Supply High Quality CAS 633-65-8 Berberine Hydrochloride Berberine HCl

Manufacturer Supply High Quality CAS 633-65-8 Berberine Hydrochloride Berberine HCl
 
Product name Berberine hydrochloride
CAS 633-65-8
Appearance white powder
Assay 99%
Storage Cool and Protect from light


Manufacturer Supply High Quality CAS 633-65-8 Berberine Hydrochloride Berberine HCl

Berberine hydrochloride
Product Name Berberine hydrochloride

CAS 633-65-8

MF C20H18ClNO4

MW 371.81

EINECS 211-195-9

MOL File 633-65-8.mol

Chemical Properties

Melting point 204-206 °C (dec.)
storage temp.  Inert atmosphere,2-8°C
solubility  methanoll: soluble
form  Yellow powder
Colour Index  75160
color  Yellow powder
Water Solubility  SOLUBLE IN COLD WATER
BRN  3836585
InChIKey VKJGBAJNNALVAV-UHFFFAOYSA-M
CAS DataBase Reference 633-65-8
EPA Substance Registry System Berberine chloride (633-65-8)


Manufacturer Supply High Quality CAS 633-65-8 Berberine Hydrochloride Berberine HCl
Usage And Synthesis
Chemical Properties

yellow crystalline powder

Uses

antiarrhythmic, alpha2 agonist, anticonvulsant, antiinflammatory, antibacterial, antifungal, antitrypanosomal, antineoplastic, immunostimulant

Uses

An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Al so inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation o f chemotherapeutic drugs.

Uses

An ingredient in some commercial eyewash products.

General Description

A highly potent and selective oxysterol EBI2 (GPR183) agonist (Kd) = 450 pM in a saturation binding assay, and EC50 = 140 pM over EC50 = 2.1 nM for its enantiomer, 7β,25-OHC, in a GTP-γS binding assay). Dose-dependently suppresses forskolin-induced cAMP accumulation in an EBI2-expressing SK-N-MC/CRE-β-galactosidase cell line (IC50 = 2 nM), but not in control cells. Stimulates migration of LPS-activated spleen B-cells and anti-CD3/CD28-activated CD4+ T-cells in a dose-dependent manner. In addition, pharmacological inhibition of its biosynthesis in vivo by Clotrimazole, a CYP7B1inhibitor, promotes the migration of adoptively transferred pre-activated B cells to the T/B boundary, mimicking the phenotype of pre-activated B cells in EBI2-deficient mice.

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.

Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.

Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.

Manufacturer Supply High Quality CAS 633-65-8 Berberine Hydrochloride Berberine HCl Manufacturer Supply High Quality CAS 633-65-8 Berberine Hydrochloride Berberine HCl Manufacturer Supply High Quality CAS 633-65-8 Berberine Hydrochloride Berberine HCl Manufacturer Supply High Quality CAS 633-65-8 Berberine Hydrochloride Berberine HCl

 

Organic Intermediate