Vb5 D-Panthenol 75% CAS. No. 81-13-0

Model NO.
food grade
Nutrient Composition
Vitamin
Resource
Chemosynthesis
The content of active substances
61%~90%
Store
Dry and Cool Place
M G
205.25
Loadign Port
Qigndao
Loading Port
Shanghai
Delivery
15days
Transport Package
25kg/Drum
Specification
FCC
Trademark
JK
Origin
China
HS Code
293624
Production Capacity
100mt/Year
Reference Price
$ 4.50 - 45.00
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Product Description





 
Product Name Vitamin B5
Part Used Herb
Appearance White Powder
Active Ingredient d panthenol 
Specification 99%

Panthenol is the alcohol analog of pantothenic acid (vitamin B5), and is thus a provitamin of B5. In organisms it is quickly oxidized to pantothenate [pantothenic acid]. Panthenol is a highly viscous transparent liquid at room temperature, but salts of pantothenic acid (for example sodium pantothenate) are powders (typically white). It is soluble in water, alcohol, propylene glycol, ether and chloroform, and slightly soluble in glycerin.

D-Panthenol is the Provitamin of D-Pantothenic acid(Vitamin B5),which plays a key role in the human intermediary metabolism.Deficiency of Vitamin B5 can result in many dermatological disorders.
D-panthenol is applied in pharmaceutical industry and almost all types of cosmetic preparations.
It cares hair,skin and nails. Role in the skin:
1.deep penetrating moisturizer
2.stimulates epithelization
3.wound healing effect
4.anti-inflammatory effect Role in the hair:

Certificate of Analysis

Batch Number Z20230412001
Production Date 2023.04.12
Batch Quantity 80 KGS
 Item Test S tandard Testing R esult
Appearance Powder Complies
Color white fine powder Complies
Particle Size 100% pass 80 mesh Complies
Oder Characteristic Complies
Taste Characteristic Complies
Loss on Drying ≤5.0% 2.20%
Residue on Ignition ≤0.1% 0.05%
Residual acetone ≤0.1% Complies
Residual Ethanol ≤0.5% Complies
Heave Mentals ≤10ppm Complies
Na ≤0.1% <0.1%
Pb ≤3 ppm Complies
Total Plate <1000CFU/g Complies
Yeast & Mold <100 CFU /g Complies
E. Coli Negative Complies
Salmonella Negative Complies
Conclusion: Conform with USP Standard

Storage:Closed container. dry & cool. keep away from moisture &strong light
Shelf life:24 Months  




Vb5 D-Panthenol 75% CAS. No. 81-13-0

 

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Dexpanthenol Basic information
Description References
Product Name: Dexpanthenol
Synonyms: 4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-(theta)-butanamid;4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-d-(+)-butyramid;Alcopan-250;Bepanthen;Bepanthene;Bepantol;Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-;Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, (R)-
CAS: 81-13-0
MF: C9H19NO4
MW: 205.25
EINECS: 201-327-3
Product Categories: Pharmaceutical Intermediates;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;ILOPAN;haircare cosmetics;Inhibitors
Mol File: 81-13-0.mol
 
 
Dexpanthenol Chemical Properties
Melting point  64~69ºC
alpha  30.5 º (c=5, H2O on anh. sub)
Boiling point  118-120 °C (2.7 mmHg)
density  1.20 g/mL at 20 °C(lit.)
refractive index  1.495-1.502
Fp  118-120°C/0.02m
storage temp.  ?20°C
pka 13.03±0.20(Predicted)
form  Viscous Liquid or Semi Solid
color  Clear colorless to slightly yellow
PH pH (100g/l,25ºC) : 8.5~10.5
optical activity [α]20/D +30±1°, c = 5% in H2O
Water Solubility  soluble
Sensitive  Hygroscopic
Merck  14,2947
BRN  1724947
InChIKey SNPLKNRPJHDVJA-ZETCQYMHSA-N
CAS DataBase Reference 81-13-0(CAS DataBase Reference)
NIST Chemistry Reference Dexpanthenol(81-13-0)
EPA Substance Registry System (+)-Panthenol (81-13-0)
 
Safety Information
Hazard Codes  Xn
Risk Statements  36/37/38-48-41-37/38-20/21/22
Safety Statements  23-24/25-45-36/37/39-26-22
WGK Germany  1
RTECS  ES4316000
F  3-10
TSCA  Yes
HS Code  29241990
Hazardous Substances Data 81-13-0(Hazardous Substances Data)
Toxicity LD50 oral in mouse: 15gm/kg
 
MSDS Information
Provider Language
(+)-Panthenol English
SigmaAldrich English
ACROS English
ALFA English
 
Dexpanthenol Usage And Synthesis
Description Dexpanthenol belongs to a derivative of pantothenic acid (vitamin B5). It can penetrate the skin and mucous membrane to be quickly oxidized to pantothenic acid. The later one is extremely hygroscopic and binds water effectively. Therefore, Dexpanthenol can be used as a moisturizer. It is added to pharmaceutical and cosmetic products to relieve itching and improve wound healing. In ointments, it can be used for the treatment of sunburns, mild burns, minor skin injuries and disorders. It is also immediately applied after major abdominal surgery to minimize the possibility of paralytic ileus. In addition, it can also be supplemented into the commercial shampoos and hair conditioners to lubricate the hair shaft and give the hair a shiny appearance. The exact mechanism of action of Dexpanthenol is still unclear, perhaps through its enhancing effect on acetylcholine.  
Chemical Properties clear colorless to slightly yellow viscous liquid
Uses cholinergic
Uses D-Panthenol is an analogue of pantothenic acid (P190300), a member of the B complex vitamins. D-Panthenol is the biologically active enantiomer of Panthenol.
Uses immunosuppressant, mitoxantrone analogue less toxic on cardiac tissue antineoplastic
Contact allergens Pan(to)thenol is the alcohol corresponding to pantothenic acid, of the vitamin B5 group. It is used as a food additive, and in skin and hair products as a conditioning agent. Contact dermatitis and urticaria have been reported.
Safety Profile Moderately toxic by intravenous route. A skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx. See also AMIDES.
Veterinary Drugs and Treatments Dexpanthenol has been suggested for use in intestinal atony or distension, postoperative retention of flatus and feces, prophylaxis and treatment of paralytic ileus after abdominal surgery or traumatic injuries, equine colic (not due to mechanical obstruction) and any other condition when there is an impairment of smooth muscle function. Controlled studies are lacking with regard to proving the efficacy of the drug for any of these indications.
Purification Methods Purify D-panthenol by distillation in vacuo. It is a slightly hygroscopic viscous oil and is soluble in H2O and organic solvents. It is hydrolysed by alkali and strong acid. [Rabin J Am Pharm Assoc (Sci Ed) 37 502 1948, Bonati & Pitré Farmaco Ed Scient 14 43 1959, Beilstein 4 IV 1652.]



Hunan JK International Trade Corporation / JK BIO-CHEM CO.,LTD is a professional exporter of food/feed additives and food /feed ingredients in China. With years of development, now we are able to provide the following food additives and food ingredients: thickeners, antioxidants, preservatives, vitamins, sweeteners, proteins, acidulants, nutritional supplements, flavours, coenzyme and so on.
Our food additives and food ingredients, especially our Ascorbic Acid (Vitamin C), Acesulfame-K, Aspartame, Citrates, Dextrose, D-Xylose, Erythorbic Acid, Fumaric Acid, Fructose,Maltodextrin, Malic Acid, Monosodium glutamate, Lactic Acid Potassium Sorbate, Sodium Erythorbate, Sodium Cyclamate, Sodium Saccharin, sodium benzoate, Sodium ascorbate, Sorbic Acid, xanthan Gum, Xylitol, Tartaric Acid, I+G, , Vanillin, Sucralose, Stevia and so on, have been exported to more than 60 countries for our good quality products.
Our staff of sales and technical support is available to help you in selecting the right protection for your application as well as to provide you with samples of our products for evaluation. At High Five, we are committed to providing the highest level of customer service, competitive pricing, speedy delivery and a comprehensive, cutting-edge product offering. Our ultimate goal is your satisfaction.





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Vb5 D-Panthenol 75% CAS. No. 81-13-0 Vb5 D-Panthenol 75% CAS. No. 81-13-0
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Our product's shelf life is 2 years, which is based on dry and ventilated storage.

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Vb5 D-Panthenol 75% CAS. No. 81-13-0 Vb5 D-Panthenol 75% CAS. No. 81-13-0 Vb5 D-Panthenol 75% CAS. No. 81-13-0 Vb5 D-Panthenol 75% CAS. No. 81-13-0 Vb5 D-Panthenol 75% CAS. No. 81-13-0




 

 

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