Pyrroloquinoline quinone (henceforth pqq) is a small quinone molecule which has the ability to be a redox agent, capable of reducing oxidants (an antioxidant effect) and then being recycled by glutathione back into an active form. It appears to be quite stable as it can undergo several thousand cycles before being used up, and it is novel since it associates with protein structures inside the cell (some antioxidants, mostly notably carotenoids like β-carotene and Astaxanthin, are located at specific areas of a cell where they exert proportionally more antioxidant effects due to proximity; PQQ seems to do this near proteins like carotenoids do so at the cell membrane).

PQQ is present in nanomolar quantities in most foods and in most animal tissuse. It promotes growth, mitochondrial function, and development in vivo and stimulates cell proliferation and viability in culture. It is a potent antioxidant that scavenges superoxide and peroxinitrite. It is neuroprotectant against 6-hydroxydopamine-induced and hypoxia/ischemia-induced neurotoxicity. PQQ conjugates to α-synuclein in vitro, inhibiting the formation of amyloid fibrils.




Applications: 
 

1.Improve the body's immune function
As a necessary factor of human development, it can stimulate the growth of cells in the body, especially the activation of human B cells, T cells, antibody production, improve the immune function of human body.PQQ is the most powerful bioactive substances so far.

2. Prevent and treat the liver damage
Can significantly reduce serum bilirubin, alanine aminotransferase levels, make liver function normal, regulate liver damage and have very good curative effect on liver disease.

3. Reduce free radical damage to human body
PQQ is a kind of oxidoreductase prosthetic group, involved in biological redox reaction in the body, can effectively remove free radicals in the body, reduce the harm of human body free radical, protect tissues, reduce the body damage caused by various diseases, such as heart disease, cancer and all kinds of inflammation.Free radicals is the source of diseases.

4. Regulate various neurological diseases
PQQ is a new kind of water-soluble vitamins, can promote the synthesis of neural factors in the human body, regulate various neurological diseases.

5. Promote the absorption of amino acids
PQQ is the prosthetic group of quinone protease, participate in the respiratory electron transport chain, in the human body through the effect of glucose, can promote the absorption of amino acids.Amino acid composition of cell SAP and synthetic protein peptide is the main raw material, is an important part of the body's biological active substances.

6. Prevent and treat the alzheimer's disease
PQQ special biological activity and physiological function but also has the repair nerve fibers, the activation of neurons, activate the dormancy of the nerve cells, can effective prevention and treatment of alzheimer's disease and improve memory.Can effectively improve intelligence.

7.Promote the synthesis of glutathione
Glutathione by glutamic acid, cysteine and glycine combination of three peptides, has an important antioxidant effect, integrating detoxification, harmful to the body poison into harmless substance, excreted in vitro, glutathione is bioactive enhancer.PQQ can promote the body's glutathione synthesis, prevent and accumulation of hepatic bilirubin in cataract.

8.Strong anticancer function
It can make the NK cells and other immune cells gathered themselves together, and play a corps of operational capability, more effectively kill tumor cells.