Product name | Pyrroloquinoline quinone |
CAS number | 72909-34-3 |
Molecular formula | C14H6N2O8 |
Molecular weight | 330.21 |
Appearance | White to beige Powder |
Purity | 99.0% |
Packge | 10gram,100gram,1KG or under requirement |
Description | Pimobendan, a novel cardiotonic vasodilator, was introduced in Japan for the treatment of acute and mild to moderate chronic heart failure. It is a phosphodiesterase inhibitor and is able to enhance sensitization of myocardial contractile regulatory protein to calcium ions. The combination of these effects contribute to its inotropic activity. In patients with severe congestive heart failure, orally administered pimobendan improves cardiac index, stroke volume index, pulmonary wedge pressure, and systemic and pulmonary vascular resistance. Pimobendan is reported to be well tolerated and largely devoid of the proarrhythmic effects of classical phosphodiesterase Ill inhibitors. Studies also suggested that combination of the inotropic agent pimobendan with an ACE inhibitor such as enalapril may be superior to monotherapy for heart failure patients.The scientific name of the PQQ pyrroloquinoline quinone (PQQ) pyrroloquinoline quinone is a new prosthetic group, is the second flavin nucleotides (FMN, FAD) and nicotinamide nucleotide (MAD NADP) in the membrane boundfound in the bacterial dehydrogenase third cofactor, the world's medical profession called fourteenth vitamins. The compound was first isolated from bacteria out, and then moving the plants have also been found, its chemical name is 4,5 - dihydro-4 ,5 - dioxide -1 - pyrrolo (2,3 f) The quinone -2,7,9-tricarboxylic acid, also known as methaxatin. PQQ as a novel water-soluble vitamins, the oxidoreductase is a cofactor, it is very rare, exist in a number of microbial, plant and animal tissues, not only involved in the catalytic-vivo redox reaction, but also has some special biological activity and physiological functions (such as shortening the stench Acetobacter [the Acetobacter rancens] and Beer yeast [Saccharomyces cerevisiae] retardation period, to stimulate early germination of tobacco seeds, prevention and treatment of certain diseases such as biological function). Trace amounts of PQQ will be able to improve the living tissue metabolism and growth performance, extremely valuable |
1.Improve the body's immune function
As a necessary factor of human development, it can stimulate the growth of cells in the body, especially the activation of human B cells, T cells, antibody production, improve the immune function of human body.PQQ is the most powerful bioactive substances so far.
2. Prevent and treat the liver damage
Can significantly reduce serum bilirubin, alanine aminotransferase levels, make liver function normal, regulate liver damage and have very good curative effect on liver disease.
3. Reduce free radical damage to human body
PQQ is a kind of oxidoreductase prosthetic group, involved in biological redox reaction in the body, can effectively remove free radicals in the body, reduce the harm of human body free radical, protect tissues, reduce the body damage caused by various diseases, such as heart disease, cancer and all kinds of inflammation.Free radicals is the source of diseases.
4. Regulate various neurological diseases
PQQ is a new kind of water-soluble vitamins, can promote the synthesis of neural factors in the human body, regulate various neurological diseases.
5. Promote the absorption of amino acids
PQQ is the prosthetic group of quinone protease, participate in the respiratory electron transport chain, in the human body through the effect of glucose, can promote the absorption of amino acids.Amino acid composition of cell SAP and synthetic protein peptide is the main raw material, is an important part of the body's biological active substances.
6. Prevent and treat the alzheimer's disease
PQQ special biological activity and physiological function but also has the repair nerve fibers, the activation of neurons, activate the dormancy of the nerve cells, can effective prevention and treatment of alzheimer's disease and improve memory.Can effectively improve intelligence.
7.Promote the synthesis of glutathione
Glutathione by glutamic acid, cysteine and glycine combination of three peptides, has an important antioxidant effect, integrating detoxification, harmful to the body poison into harmless substance, excreted in vitro, glutathione is bioactive enhancer.PQQ can promote the body's glutathione synthesis, prevent and accumulation of hepatic bilirubin in cataract.
8.Strong anticancer function
It can make the NK cells and other immune cells gathered themselves together, and play a corps of operational capability, more effectively kill tumor cells.