Product name | 5-Amino-1MQ |
CAS no. | 42464-96-0 |
Molecular FormulaN/a | N/a |
Molecular Weight | N/a |
5-Amino-1MQ is a small molecule that blocks the activity of the enzyme called nicotinamide N-methyltransferase
(NNMT). NNMT is a very important component in metabolism and energy and is predominantly active in fat tissue.
By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor
that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1).
SIRT1 is also known as the "longevity gene" because of its role in reducing the risk of diabetes, obesity, metabolic
syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration,
and cancer. According to research in mice given 5-amino-1MQ showed a 7% reduction in body mass without any
changes in food intake, compared to controls. Research has shown that decreasing NNMT may help shrink fat cells
and reduce the size of fat deposits.
Benefits of 5-Amino-1MQ
In addition to aiding weight loss, 5-amino-1MQ may exert the following beneficial effects in those who take it through
supplementation: