Product Information
Products Name
:
Melanotan II
CAS No.
: 121062-08-6
Purity
: >99.0%
Molecular Formula
: C50H69N15O9
Molecular Weight
: 1024.2g/mol
Sequence
: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH2
Appearance
: White Lyophilized powder
Reconstitution
: Required
Storage
:After reconstitution store at 2°C - 8°C
Description:
What is Melanotan II?
Melanotan II (CAS NO.121062-08-6) was first synthesized at the University of Arizona. Researchers decided to find a more potent and stable alternative, one that would be more practical to defend against skin cancer.
The researchers headed by Victor Hruby found a peptide, [Nle4, D-Phe7]-α-MSH, that was approximately 1,000 times more potent than natural α-MSH after synthesizing and
screening hundreds of molecules. They dubbed this new peptide, "Melanotan" (later Melanotan I, now known as afamelanotide). They subsequently developed another analog, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2), which they named "Melanotan
Acetate".
Since their discovery, numerous studies dating back to the mid-1980s have found no obvious toxic effects of the Melanotan peptides. The scientists hoped to use Melanotan peptides to combat melanoma by stimulating the body's natural tanning mechanism to create a tan without first needing exposure to harmful levels of UV radiation. This in turn, they hypothesized, could reduce the potential for skin damage that can eventually lead to skin cancer.