Ethyl 2-oxocyclohexanecarboxylate Chemical Properties |
Melting point | 101 °C |
Boiling point | 106 °C/11 mmHg (lit.) |
density | 1.064 g/mL at 25 °C (lit.) |
refractive index | n 20/D 1.477(lit.) |
Fp | 185 °F |
storage temp. | Inert atmosphere,Room Temperature |
pka | 12.06±0.20(Predicted) |
Water Solubility | Soluble in water. |
BRN | 608356 |
CAS DataBase Reference | 1655-07-8(CAS DataBase Reference) |
NIST Chemistry Reference | Cyclohexanecarboxylic acid, 2-oxo-, ethyl ester(1655-07-8) |
EPA Substance Registry System | Cyclohexanecarboxylic acid, 2-oxo-, ethyl ester (1655-07-8) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 23-24/25-37/39-26-36 |
WGK Germany | 3 |
TSCA | Yes |
HazardClass | IRRITANT |
HS Code | 29183000 |
Ethyl 2-oxocyclohexanecarboxylate Usage And Synthesis |
Chemical Properties | Clear colorless to pale yellow liquid |
Uses | Ethyl 2-oxocyclohexanecarboxylate is used to produce other chemicals. For example, it can react with 4-methyl-aniline to get 2-oxo-cyclohexanecarboxylic acid p-toluidide. The reaction occurs with reagent DMAP |
Uses | Ethyl 2-Oxocyclohexanecarboxylate is used in biocatalysis. |
Synthesis Reference(s) |
Canadian Journal of Chemistry, 42, p. 1333, 1964
DOI:
10.1139/v64-205
The Journal of Organic Chemistry, 53, p. 878, 1988 DOI: 10.1021/jo00239a038 Tetrahedron Letters, 7, p. 2201, 1966 |