2-Dimethylamino hydrochloride Basic information |
Product Name: | 2-Dimethylamino hydrochloride |
Synonyms: | 2-DIMETHYLAMINO HCL;2-DIMETHYLAMINO HYDROCHLORIDE;2-DMPC;2-CHLORO-1-DIMETHYLAMINOPROPANE HYDROCHLORIDE;2 CHLORO-N,N-DIMETHYLPROPANAMINE HYDROCHLORIDE;2-CHLORO-N,N-DIMETHYLPROPYLAMINE HYDROCHLORIDE;2-CHLOROPROPYLDIMETHYLAMMONIUM CHLORIDE;N-(2-Chloropropyl) hydrochloride |
CAS: | 4584-49-0 |
MF: | C5H13Cl2N |
MW: | 158.07 |
EINECS: | 224-971-7 |
Product Categories: | Amine Salts ; Building Blocks ; Chemical Synthesis ; Nitrogen Compounds ; Organic Building Blocks |
Mol File: | 4584-49-0.mol |
2-Dimethylamino hydrochloride Chemical Properties |
Melting point | 187-190 °C(lit.) |
storage temp. | Store below +30°C. |
solubility | 2000g/l |
form | Crystalline Powder |
color | White to light cream |
PH | 5-6 (500g/l, H2O, 20ºC) |
Water Solubility | 2000 g/L (20 º C) |
Sensitive | Hygroscopic |
BRN | 3670215 |
InChIKey | OCWGRWAYARCRTQ-UHFFFAOYSA-N |
CAS DataBase Reference | 4584-49-0(CAS DataBase Reference) |
EPA Substance Registry System | 2-Chloro-N,N-dimethyl-1-propanamine hydrochloride (4584-49-0) |
Safety Information |
Hazard Codes | Xn,Xi |
Risk Statements | 22-36/37/38 |
Safety Statements | 26-36 |
RIDADR | 2811 |
WGK Germany | 3 |
RTECS | TY1225000 |
TSCA | Yes |
HazardClass | 6.1(b) |
PackingGroup | III |
HS Code | 29211980 |
2-Dimethylamino hydrochloride Usage And Synthesis |
Chemical Properties | Colourless to pale beige crystalline powder |
Uses |
2-Chloro-N,N-dimethylpropylamine hydrochloride (DMIC) is used as intermediate for the syntheses of pharmaceuticals (e.g. isothipendyl,
promethazine) |
Uses | Hydrochloride salt of 2-Dimethylamino, used in the synthesis of analogues of lipophilic chalcones, which act as antitubercular agents. |
General Description | Off-white chunky solid. |
Air & Water Reactions | 2-Dimethylamino hydrochloride is hygroscopic. Soluble in water. |
Reactivity Profile | 2-Dimethylamino hydrochloride is incompatible with strong oxidizing agents. . Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. |
Fire Hazard | Flash point data for 2-Dimethylamino hydrochloride are not available; however, 2-Dimethylamino hydrochloride is probably combustible. |
Synthesis |
Following the procedure of Schultz and Sprague, J. Am. Chem. Soc., 70, 48 (1948), A solution of 5.72 g. of freshly distilled thionylchloride in 2 ml. was added thereto. The reaction mixture was allowed to come to ambient temperature over a period of about 30 minutes and was then heated to refluxing temperature for an additional 30 minutes. The precipitated material redissolved on heating. 1-Dimethylamino-2-chloropropane hydrochloride began to crystallize from the boiling solvent. The reaction mixture was cooled, diluted with ether and filtered. The reaction product comprising 1-dimethylamino-2-chloropropane hydrochloride weighed about 5.5 g. (95 percent yield). Recrystallization yielded purified 1-dimethylamino-2-chloropropane hydrochloride melting at 192°-194° C. |
2-Dimethylamino hydrochloride Preparation Products And Raw materials |
Packing Method:
Shipping Transit could be DHL.UPSTNT EMS Fedex and so on. For mass orders,it will be delivered by air or sea. Depending on your location,please allow 1-5 business days for your order to arrive. For small order please expect 3-7 days by UPS DHL EMS, For mass order,please allow 5-8 days by Air15-30 days by Sea.
Q1:Are you trading company or manufacturer?
A1:We are chemical factory in China,So we can provide wholesale price.
Q2:How can I get the samples?
A2:We can provide you free sample for our existing products, the lead time is about 1-2 days. You just need to pay the sample delivery cost.
Q3:If the inspection result can not meet the agreement between the two sides, can you bear all the losses caused by this?
A3:Yes, we can. We guarantee that the samples provided will meet the needs of our clients and we will bear the risk of default.
Q4:How long is your delivery time?
A4:Generally it is with 5 days if the goods are in stock. According to quantity your required, the delivery time may
slightlychange.
Q5:What's your terms of payment?
A5:We can accept various payment methods, western union, T/T, BTC( bitcoin)etc.