Introduction of   Lidoca ine
 
Lido caine acts as a local anesthetic by reversibly blocking sodium channels and blocking the transmission of action potentials along nerve fibers. Sensory fibers are blocked earlier than motor fibers, so low doses of lido caine can act as a selective sensory block.   Lid ocaine also has antiarrhythmic effects, belonging to class I and b antiarrhythmic drugs.



Application of   Lid ocaine

 

Lido caine is the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias if amiodarone is not available or contraindicated.

Lidoc aine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine prophylactic administration is no longer recommended for acute cardiac infarction; the overall benefit of this measure is not convincing.