Dyclonine (Dyclocaine) is an oral anaesthetic that is the active ingredient of Sucrets, an over the counter throat lozenge. It is also found in some varieties of the Cepacol sore throat spray. It is a local anesthetic, used topically as the hydrochloride salt.

Dyclonine hydrochloride (also known as daclone hydrochloride, chemical name 4-butoxy-β-piperidinyl propiop hydrochloride, is a fast onset, long duration of action, adverse reactions, safety High local anesthetic. Clinical for mucosal surface anesthesia and skin pain, itching.
 

The main mechanism of action is nerve block, local anesthesia fast, strong pharmacological effects and long duration, small toxicity, analgesic, antipruritic, bactericidal effect.

Function & Application

Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading to an increased threshold for excitation. This reversibly stabilizes the membrane and inhibits depolarization, leading to the failure of a propagated action potential and subsequent conduction

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