Good Quality Pazopanib Powder CAS 444731-52-6 Pazopanib with Best Price

Model NO.
CAS 444731-52-6
Colour
White
MOQ
10 Gram
Shipping Method
UPS, FedEx, TNT, EMS Ect
Delivery Time
Within 24 Hours After Receiving The Payment
Grade
Pharmaceutical Grade
Customized
Non-Customized
Certificate
GMP, ISO 9001
Suitable for
Adult
Payment Ways
Western Union, Money Gram, Bitcoin and T/T
Storage Temp.
Store at Rt
Melting Point
285-289°c (DEC.)
Other Name
Pazopanib Powder
Molecular Weight
437.52
Product Name
Pazopanib
Usage
Metastatic Renal Cell Carcinoma
Purity
99%Min
Transport Package
Foil Bag
Specification
1kg/bag
Trademark
yuanmeng
Origin
China
HS Code
2934990002
Production Capacity
1000kg/Month
Reference Price
Please contact us for quote
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Product Description

Product Description

Product Name: Pazopanib
Synonyms: Pazopanib for research;5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;Pazopanib;CS-1857;Pazopanib (free base) (GW786034, Votrient);Pazopanib(GW786034);5-(4-((2,3-diMethyl-3,3a-dihydro-2H-indazol-6-yl)(Methyl)aMino)pyriMidin-2-ylaMino)-2-MethylbenzenesulfonaMide;5-[(4-{[(2,3-diMethyl-2H-indazol-6-yl)Methyl]aMino}pyriMidin-2-yl)aMino]-2-Methylbenzene-1-sulfonaMide
CAS: 444731-52-6
MF: C21H23N7O2S
MW: 437.52
EINECS: 639-683-0

Melting point: 285-289°C (dec.)
Boiling point: 728.8±70.0 °C
Density: 1.40
Storage temp.: Store at RT
Appearance: White Powder

Description:

Pazopanib is a multi-kinase inhibitor that inhibits the VE GF receptors VE GFR1, VE GFR2, and VE GFR3 (IC50s = 10, 30, and 47 nM, respectively, in a cell-free enzyme assay). It also inhibits PDGFRα, PDGFRβ, and c-Kit (IC50s = 71, 84, and 74 nM, respectively, in a cell-free enzyme assay) as well as additional receptor tyrosine kinases. Pazopanib inhibits upregulation of the surface adhesion proteins ICAM-1 and VCAM-1 induced by VE GF in multiple myeloma cells cocultured with human umbilical vein endothelial cells (HUVECs) and decreases multiple myeloma cell adhesion to HUVECs. It also inhibits proliferation of multiple myeloma cells cocultured with HUVECs. Pazopanib (30 and 100 mg) reduces tumor growth, induces apoptosis, decreases angiogenesis, and increases survival in a multiple myeloma mouse xenograft model. Formulations containing pazopanib have been used in the treatment of cancer.

Uses:

Tyrosine kinase inhibitor:
Treatment of metastatic renal cell carcinoma and soft tissue sarcoma

Detailed Photos

Good Quality Pazopanib Powder CAS 444731-52-6 Pazopanib with Best Price
Good Quality Pazopanib Powder CAS 444731-52-6 Pazopanib with Best Price
 

Packaging & Shipping

Good Quality Pazopanib Powder CAS 444731-52-6 Pazopanib with Best Price Good Quality Pazopanib Powder CAS 444731-52-6 Pazopanib with Best Price

Good Quality Pazopanib Powder CAS 444731-52-6 Pazopanib with Best Price
 

Our Advantages

1. Rich experience: Our company is a professional production leading factory in China in pharmaceutical area of many years. 

2. Top quality: High quality guaranteed, once any problem is found, the package would be reshipped for you .

3. Security Shipping: Shipping by express (FedEx,UPS,DHL,EMS), by air. The most professional forwarder would be recommanded for you.

4. Fast delivery: We have stock, so we can delivery quickly once payment is received.

5. Quality service: We will give you warm after-sale service,if any question we will reply you within 24 hours.

6. Competitive prices: A discount would be given when you make a large order.

Order Process and Tips

 

Make an order Please make clear what product and what quantity you need
Quote Prices and Specifications details would be offered for you to consider and confirm
Payment ways Bank Transfer, Western Union, Money Gram and Bitcoin
Delivery ways All Express Modes(EMS, DHL, TNT, FedEx, UPS, etc.)
Shipping address Provide your Valid and Correct destination address info(if possible with post code, phone number).
Packing Select best ways according to quantity and safety degree(Super discreet, professional and experienced)
Lead time Within 8 hours upon receipt of payment
Package picture Photos of package would be offered to tell apart the items
Tracking number Offered once it is released
Shipping time 3-7 working days (Door-to-Door)
After-sale service 24/7 Online for any problems
 

About Us

Our factory:

Good Quality Pazopanib Powder CAS 444731-52-6 Pazopanib with Best Price
Our laboratory:

Good Quality Pazopanib Powder CAS 444731-52-6 Pazopanib with Best Price
Our warehouse:



Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect.

Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other areas in the world. We have established close and stable cooperative relationships with over 200 domestic pharmaceutical and chemical enterprises. With high quality and favorable price, we′ re pleased to get your inquiry and we will reply you as soon as possible.

We will continue to forge ahead and strive hard for excellence, keep on exploring and progressing to develop more high-tech products with superior quality, to satisfy increasing demand of the clients, and create more value for our partners!


Contact us!

Hubei Yuanmeng Biological Technology Co., Ltd.
Room 3820, Building 2, Vanke Golden City, Hongshan District, Wuhan, Hubei, China
Fiona Wei / Sales Manager
 
 
 

 

Organic Intermediate