Pain Relief Peptide Ara290 Cibinetide Acetate CAS: 1208243-50-8 5mg 10mg 15mg/Vial

Model NO.
CAS: 1208243-50-8
Transport Package
Bag /Drum
Specification
1kg/bag, 25 kg/drum, customised
Trademark
SZK Biotech
Origin
China
HS Code
3912390000
Production Capacity
5 Ton/ Month
Reference Price
$ 4.50 - 9.00
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Product Description

 

Product Description

Detailed Product Information
 
Product Name:   ARA290
Chemical   Name : Cibinetide Acetate
CAS No.:  1208243-50-8
Sequence: H-Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-OH
Molecular Formula: C51H84N16O21
Molecular Weight: 1257.3 g/mol
Purity :   9 8 %   HPLC
Appearance:     White Lyophilized Powder
Typical use :   Immune modulation
Shelf Life  : 6month
Storage : Room temperature away from light

Description:

ARA-290 inhibits macrophage activation. Thus it enhances the survival and proliferation of transplanted islet cells in diabetic patients. Islet cell transplant has been considered as the holy grail of endocrinology for the treatment of chronic diabetes. Islet cell transplant allows for physiological control of blood sugar and helps to avoid the long-term adverse effects of insuli usage. However, the host immune response leads to the death of the transplanted islet cells. ARA-290 suppresses the pro-inflammatory cytokines such as IL-6, IL-2, and TNF-Alpha and allows for an acceptance of the graft.
ARA-290 has been observed to bind to the tissue-protective receptor (TPR) on the cell surface and mediate protective response against inflammatory cytokines, thereby modulating the immune system response. EPO can also interact with TPR but is not a suitable drug candidate due to its cardiovascular ad hematopoietic side effects. ARA-290 mediates the positive responses of EPO while avoiding the adverse effects. This results in reduced cellular apoptosis and lower levels of inflammatory cytokines. Thus the tissue survival and proliferation significantly improve. This function leads to faster wound healing, recovery, decreased mortality and morbidity, reduced scar formation, and rapid post-injury recovery of function.

The immune system is known to regulate the sensation of pain, especially neuropathic pain. Neuropathic pain is very difficult to treat, like in diabetes. Targeting the innate repair receptor (IRR) helps to alleviate the pain. ARA-290 has been shown to bind to IRR and therefore proves to be of value. The peptide not only binds to IRR but also inhibits TRPV1 channel activity. TRPV1channel is also known as capsaicin receptor, which induces the perception of heat associated with neuropathic pain. Hence the peptide can control pain associated with amputation, chemotherapy, multiple sclerosis, and diabetes.
Small nerve fiber loss is prevalent in diseases like HIV, diabetes, celiac disease, thyroid dysfunction, and more. The small nerve fibers in the skin lead to pain and heat sensation. The onset of neuropathy leads to a burning sensation in the region affected. The peptide has proven fruitful in controlling neuropathy.

Pain Relief Peptide Ara290 Cibinetide Acetate CAS: 1208243-50-8 5mg 10mg 15mg/Vial Pain Relief Peptide Ara290 Cibinetide Acetate CAS: 1208243-50-8 5mg 10mg 15mg/Vial Pain Relief Peptide Ara290 Cibinetide Acetate CAS: 1208243-50-8 5mg 10mg 15mg/Vial

 

 

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Packaging & Shipping

Pain Relief Peptide Ara290 Cibinetide Acetate CAS: 1208243-50-8 5mg 10mg 15mg/Vial
You can specify the package . Liquid  is regularly packed in drip proof vacuum sealed  plastic bottle /drum .


Pain Relief Peptide Ara290 Cibinetide Acetate CAS: 1208243-50-8 5mg 10mg 15mg/Vial
 

 

 

You can specify delivery way .We are okay with DHL /Fedex/TNT/UPS/EMS or by ship or air 

Lead time :  Peak season 4-8 days ,off season  3-7days  after payment

We have rich experience in customer clearance  to Asian countries, USA ,EU,Canada , safe and fast  delivery door to door .


Pain Relief Peptide Ara290 Cibinetide Acetate CAS: 1208243-50-8 5mg 10mg 15mg/Vial
 

Payment

Pain Relief Peptide Ara290 Cibinetide Acetate CAS: 1208243-50-8 5mg 10mg 15mg/Vial

 

FAQ

FAQ
Q1 Can i get some samples
A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2 How to start orders or make payments
A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information.
Payment by T/T, Western Union or Paypal or Escrow(Alibaba).
Q3 How to confirm the Product Quality before placing orders
A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4 What's your MOQ
A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5 How about delivery leadtime
A5 Delivery lead time: About 1-3days after payment confirmed. (Chinese holiday not included)
Q6 Is there a discount
A6 Different quantity has different discount.
Q7 How do you treat quality complaint
A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
GUARANTEE QUALITY OF EACH PRODUCT !

Company Profile

       As an researcher and manufacturer  of pharmaceutuical intermediate , Shengzhikai  Biotech  is one of the China's high-performance pharmaceutical intermediate  products suppliers. It covers 4 popular research fields including pharmaceutical  intermediate  , plant extract ,chemical reagent and chemical  intermediate .Existing compounds are continuously expanded to meet the latest research needs.

      For pharmaceutical intermediate , Shengzhikai  has good purity, stability activity. Our core philosophy is "guarantee the quality of each product" and is committed to providing comprehensive research materials and reliable product performance for medical research. The products have been widely used by customers around the world. Shengzhikai's mission is to make it easier for scientists around the world to access the most effective intermediate  and help them make major scientific discoveries faster. These compounds have a wide range of applications in pharmaceutical  studies of human diseases and have a wide range of potential uses.

      Shengzhikai   established stable relationships with many customers. It's main customers include the world's major pharmaceutical companies, biotechnology companies, hospitals and major clinical diagnostic laboratories. Universities, research institutes, and government agencies.
 

Pain Relief Peptide Ara290 Cibinetide Acetate CAS: 1208243-50-8 5mg 10mg 15mg/Vial

 


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