Livagen (Lys-Glu-Asp-Ala) Peptide 20mg with High Purity

Model NO.
Livagen
Colour
White
Lead Time
10-15days
Transport Package
1kg
Specification
99%
Trademark
senwayer
Origin
China
Production Capacity
10000kg/Month
Reference Price
$ 54.00 - 90.00
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Product Description

    
Product Description
The effect of new peptide bioregulators--Livagen (Lys-Glu-Asp-Ala) and Epitalon (Ala-Glu-Asp-Gly)--on endogenous opioid system was studied, particularly, their ability to change the activity of enkephalin-degrading enzymes from serum and interact with opioid receptors of the brain membrane fraction. Enkephalinase activity was assayed in vitro by the rate of 3H-Leu-enkephalin hydrolysis in the presence of the tested peptides. Livagen and Epitalon inhibited enkephalin-degrading enzymes from human serum. Livagen proved to be more efficient also as compared to well-known peptidase inhibitors such as puromycin, leupeptin, and D-PAM. The dose-inhibitory effect curves for Livagen and Epitalon were plotted; their IC50 equaled 20 and 500 microM, respectively. The interaction between the peptides and opioid receptors was estimated using a radioreceptor method with [3H][D-Ala2, D-Leu5]-enkephalin. No interaction was observed between the tested peptides and mu- or delta-opioid receptors of the membrane fraction from the rat brain.
 
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Livagen (Lys-Glu-Asp-Ala) Peptide 20mg with High Purity

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Livagen (Lys-Glu-Asp-Ala) Peptide 20mg with High Purity

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Livagen (Lys-Glu-Asp-Ala) Peptide 20mg with High Purity
Livagen (Lys-Glu-Asp-Ala) Peptide 20mg with High Purity

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Livagen (Lys-Glu-Asp-Ala) Peptide 20mg with High Purity Livagen (Lys-Glu-Asp-Ala) Peptide 20mg with High Purity
 

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Livagen (Lys-Glu-Asp-Ala) Peptide 20mg with High Purity

 

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Livagen (Lys-Glu-Asp-Ala) Peptide 20mg with High Purity

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