Product Information
Products Name
: KISSPEPTIN-10
Trade Name:
KP-10 peptide
CAS No.
:
374675-21-5
Purity
:
>98.0%
Molecular Formula
:
C63H83N17O14
Molecular Weight
:
1302.44g/mol
Sequence:
H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Application:
Nootropics Peptides
Appearance
:
White Lyophilized powder
Reconstitution
:
Required
Storage
:
After reconstitution store at 2°C - 8°C
Description:
WHAT IS Kisspeptin-10?
Kisspeptin was originally identified as a human metastasis suppressor gene that has the ability to suppress melanoma and breast cancer metastasis. Kisspeptin-GPR54 signaling has an important role in initiating secretion of gonadotropin-releasing hormone (GnRH) at puberty from the anterior pituitary.
This peptide sequence is found in residues 45 to 54 of Metastin (also referred to as Kisspeptin-10). This peptide increases plasma concentrations of GH and LH in prepubertal dairy heifers. This peptide is the minimal sequence needed to activate GPR54 signaling, which may function in negatively regulating CXCR4's role in programming tumor metastasis. Specifically, Kisspeptin-10 inhibits signaling and chemotaxis induced by SDF-1.