Estradiol valerate is an organic compound with the chemical formula of C23H32O3. It is the valerate ester of estradiol. Its action is similar to that of estradiol. It is a long-term estrogen preparation, which can last for 2 weeks after injection. It has a positive and negative feedback regulatory effect on the hypothalamus pituitary gland, indirectly affecting follicular development and ovulation; Promote the development of female sexual organs and Secondary sex characteristic; Promote endometrial hyperplasia and repair, and promote the proliferation of cervical glandular epithelial cells. Increase the secretion of cervical mucus, which helps sperm penetrate. It can improve menopausal symptoms and reduce the incidence of osteoporosis and cardiovascular disease in menopausal women.