Melting point | 192-193 °C(Solv: eth yl acetate (1 41-78-6)) |
Boiling point | 55-60 °C11 mm Hg(lit.) |
density | 0.92 g/mL at 25 °C (lit.) |
refractive index | n 20/D 1.460 |
Fp | 140 °F |
storage temp. | Store below +30°C. |
pka | 8.02±0.20(Predicted) |
form | Liquid |
color | Clear yellow to orange |
Specific Gravity | 0.92 |
PH | 12 (100g/l, H2O, 20ºC) |
Water Solubility | MISCIBLE |
Sensitive | Air Sensitive |
BRN | 106924 |
CAS DataBase Reference | 1445-73-4(CAS DataBase Reference) |
NIST Chemistry Reference | 4-Piperidinone, 1-methyl-(1445-73-4) |
Safety Information |
Hazard Codes | C,Xi |
Risk Statements | 34-10-36/37/38 |
Safety Statements | 23-24/25-37/39-26 |
RIDADR | UN 1224 3/PG 3 |
WGK Germany | 3 |
Hazard Note | Irritant |
HazardClass | 3 |
PackingGroup | III |
HS Code | 29333999 |
1-Methyl-4-piperidone Usage And Synthesis |
Chemical Properties | clear yellow to orange liquid |
Purification Methods | It is best purified by fractional distillation The hydrochloride of the hydrate (4-diol) has m 94.7-95.5o, but the anhydrous hydrochloride which crystallises from CHCl3/Et2O has m 165-168o (164-167o) and can also be obtained by sublimation at 120o/2mm. The oxime has m 130-132o (from Me2CO). The methiodide crystallises from MeOH, the crystals with 1MeOH have m 189-190o, and the solvent-free iodide has m 202-204o(dec). [Lyle et al. J Org Chem 24 342 1959, Bowden & Greeen J Chem Soc 1164 1952, Tomita Yakugaku Zasshi (J Pharm Soc Japan) 71 1053 1951, Beilstein 21 IIII/IV 3183, 21/6 V 419.] |
1-Methyl-4-piperidone Preparation Products And Raw materials |