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Manufacturer Supply High Quality CAS 55-22-1 Isonicotinic Acid
Model NO.
TY-02AL
Colour
White
Package
Foil Bag
Place
China
Assay
99%
Shelf
2 Years
Transport Package
25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
Please contact us for quote
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Description
Product Description
Product name
Isonicotinic acid
CAS
55-22-1
Appearance
white powder
Assay
99%
Storage
Cool and Protect from light
Isonicotinic acid
Product Name Isonicotinic acid
CAS 55-22-1
MF C6H5NO2
MW 123.11
EINECS 200-228-2
MOL File 55-22-1.mol
Chemical Properties
Melting point ≥300 °C (lit.)
Boiling point 260 °C (15 mmHg)
Density 1,47g/cm
refractive index 1.5423 (estimate)
Flash point 260°C/15mm
storage temp. no restrictions.
solubility 6g/l
pka 4.96(at 25ºC)
form powder
color yellow to tan
PH 3-4 (6g/l, H2O, 20ºC)(saturated solution)
Water Solubility 5.2 g/L (20 ºC)
Merck 14,5187
BRN 109599
InChIKey TWBYWOBDOCUKOW-UHFFFAOYSA-N
CAS DataBase Reference 55-22-1(CAS DataBase Reference)
NIST Chemistry Reference Isonicotinic acid(55-22-1)
EPA Substance Registry System Isonicotinic acid (55-22-1)
Usage And Synthesis
Chemical Properties
white to light yellow crystal powder
Uses
Isonicotinic acid is a metabolite of isoniazid. It is an isomer of nicotinic acid. The chronic toxicity of isonicotinic acid is slightly higher than that of isonicotinic acid hydrazide ( INH ) .
Isonicotinic acid is a moderately basic compound (based on its pKa). Isonicotinic acid is an organic compound with a carboxyl group on a pyridinee ring. The carboxyl group for isonicotinic acid is on the 4-position instead of the 3-position for nicotinic acid. It is an isomer of nicotinic acid. Isonicotinic acid is a metabolite of isoniazid.
Isonicotinic acid considered to be inactive isomer of nicotinic acid. Isonicotinic acid is a metabolite of pyridinee-4-carboxy hydrazide (isonicotinyl hydrazide; isoniazid) a front-line weapon in the battle against tuberculosis. Isonicotinic acid and its derivatives are used in manufacturing pharmaceuticals and agrochemicals.
Used in the biological study of differentiation induced by nicotinic acid, nicotinamide and isonicotinic acid in human leukemia cell lines
Uses
Isonicotinic acid (IN) can be used as:
An organocatalyst in the one pot four component condensation reaction, to synthesize pyranopyrazoles based heterocyclic compounds.
An organic ligand for the preparation of copper(I) halide coordination polymer [CuBr(IN)]n, by hydrothermal method.
As a starting material for the synthesis of cation-dimers with potent antimalarial activity.
GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
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